Neuroimaging in Functional Movement Disorders.


Journal

Current neurology and neuroscience reports
ISSN: 1534-6293
Titre abrégé: Curr Neurol Neurosci Rep
Pays: United States
ID NLM: 100931790

Informations de publication

Date de publication:
12 02 2019
Historique:
entrez: 13 2 2019
pubmed: 13 2 2019
medline: 18 2 2020
Statut: epublish

Résumé

Functional movement disorders are common and disabling causes of abnormal movement control. Here, we review the current state of the evidence on the use of neuroimaging in Functional movement disorders, particularly its role in helping to unravel the pathophysiology of this enigmatic condition. In recent years, there has been a shift in thinking about functional movement disorder, away from a focus on high-level psychological precipitants as in Freudian conversion theories, or even an implicit belief they are 'put-on' for secondary gain. New research has emphasised novel neurobiological models incorporating emotional processing, self-representation and agency. Neuroimaging has provided new insights into functional movement disorders, supporting emerging neurobiological theories implicating dysfunctional emotional processing, self-image and sense of agency. Recent studies have also found subtle structural brain changes in patients with functional disorders, arguing against a strict functional/structural dichotomy.

Identifiants

pubmed: 30747347
doi: 10.1007/s11910-019-0926-y
pii: 10.1007/s11910-019-0926-y
pmc: PMC6373326
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

12

Subventions

Organisme : Medical Research Council
ID : MR/M02363X/1
Pays : United Kingdom

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Auteurs

Jacob J Roelofs (JJ)

Southmead Hospital, North Bristol NHS Trust, Bristol, UK.
Neuroscience Research Centre, Institute of Molecular and Clinical Sciences, St George's University of London;, Cranmer Terrace, London, SW17 0QT, UK.

Tiago Teodoro (T)

Neuroscience Research Centre, Institute of Molecular and Clinical Sciences, St George's University of London;, Cranmer Terrace, London, SW17 0QT, UK.
Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Universidade de Lisboa, Lisbon, Portugal.

Mark J Edwards (MJ)

Neuroscience Research Centre, Institute of Molecular and Clinical Sciences, St George's University of London;, Cranmer Terrace, London, SW17 0QT, UK. medwards@sgul.ac.uk.
Atkinson Morley Regional Neuroscience Centre, St George's University Hospitals, London, UK. medwards@sgul.ac.uk.

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Classifications MeSH