Tidal volume transmission during non-synchronized nasal intermittent positive pressure ventilation via RAM
Journal
Journal of perinatology : official journal of the California Perinatal Association
ISSN: 1476-5543
Titre abrégé: J Perinatol
Pays: United States
ID NLM: 8501884
Informations de publication
Date de publication:
05 2019
05 2019
Historique:
received:
05
11
2018
accepted:
14
01
2019
revised:
08
01
2019
pubmed:
14
2
2019
medline:
20
5
2020
entrez:
14
2
2019
Statut:
ppublish
Résumé
Nasal intermittent positive pressure ventilation (NIPPV) is a widely used mode of support in neonates, during which ventilator inflations may or may not coincide with spontaneous breathing. We tested the hypothesis that inflations delivered with NIPPV via RAM Fourteen subjects were monitored while receiving NIPPV. We compared tidal volumes during ventilator-supported breaths, unsupported breaths, and ventilator inflations not accompanied by patient effort (defined using electrical activity of the diaphragm). Mean tidal volumes in arbitrary units were 0.30 ± 0.22 in NIPPV inflations associated with patient effort and 0.27 ± 0.15 in spontaneous breaths without ventilator assistance (p = 0.82). Tidal volumes during ventilator-only inflations were 0.06 ± 0.04 (p < 0.005 vs. both ventilator-assisted and unassisted efforts). NIPPV via RAM cannula produces minimal, clinically insignificant tidal volumes during non-spontaneous inflations.
Sections du résumé
BACKGROUND
Nasal intermittent positive pressure ventilation (NIPPV) is a widely used mode of support in neonates, during which ventilator inflations may or may not coincide with spontaneous breathing.
OBJECTIVE
We tested the hypothesis that inflations delivered with NIPPV via RAM
DESIGN/METHODS
Fourteen subjects were monitored while receiving NIPPV. We compared tidal volumes during ventilator-supported breaths, unsupported breaths, and ventilator inflations not accompanied by patient effort (defined using electrical activity of the diaphragm).
RESULTS
Mean tidal volumes in arbitrary units were 0.30 ± 0.22 in NIPPV inflations associated with patient effort and 0.27 ± 0.15 in spontaneous breaths without ventilator assistance (p = 0.82). Tidal volumes during ventilator-only inflations were 0.06 ± 0.04 (p < 0.005 vs. both ventilator-assisted and unassisted efforts).
CONCLUSIONS
NIPPV via RAM cannula produces minimal, clinically insignificant tidal volumes during non-spontaneous inflations.
Identifiants
pubmed: 30755718
doi: 10.1038/s41372-019-0333-x
pii: 10.1038/s41372-019-0333-x
doi:
Types de publication
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM