Diabetes control could through platelet-to-lymphocyte ratio in hemograms.


Journal

Revista da Associacao Medica Brasileira (1992)
ISSN: 1806-9282
Titre abrégé: Rev Assoc Med Bras (1992)
Pays: Brazil
ID NLM: 9308586

Informations de publication

Date de publication:
Jan 2019
Historique:
received: 15 01 2018
accepted: 20 01 2018
entrez: 14 2 2019
pubmed: 14 2 2019
medline: 13 3 2019
Statut: ppublish

Résumé

Association between type 2 diabetes mellitus and inflammation is well-established. We aimed to study platelet-to-lymphocyte ratio (PLR), a novel inflammatory index derived from hemogram, in diabetic patients in comparison to those in healthy volunteers. Medical data of type 2 diabetics that showed up in general outpatient medical clinics of our institution between February 2017 and August 2017 were recorded and analyzed. Median PLR of type 2 diabetic patients was significantly higher than the PLR of healthy controls (p=0.001). Moreover, PLR was significantly and positively correlated with HbA1c (p<0.001, r=0.58), fasting plasma glucose (p<0.001, r=0.49), and c-reactive protein (p=0.003, r=0.30) levels. Type 2 diabetic subjects with proteinuria had significantly higher PLR levels than that of diabetic subjects without proteinuria. As an inexpensive and easy to use index, PLR may be useful in predicting the development and control levels of type 2 diabetes mellitus. However, its correlation with HbA1c needs to be validated by larger prospective studies.

Identifiants

pubmed: 30758418
pii: S0104-42302019000100038
doi: 10.1590/1806-9282.65.1.38
pii:
doi:

Substances chimiques

Biomarkers 0
C-Reactive Protein 9007-41-4

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

38-42

Auteurs

Burcin Atak (B)

Abant Izzet Baysal University Hospital, Department of Internal Medicine, Bolu, Turkey.

Gulali Aktas (G)

Abant Izzet Baysal University Hospital, Department of Internal Medicine, Bolu, Turkey.

Tuba T Duman (TT)

Abant Izzet Baysal University Hospital, Department of Internal Medicine, Bolu, Turkey.

Edip Erkus (E)

Abant Izzet Baysal University Hospital, Department of Internal Medicine, Bolu, Turkey.

M Zahid Kocak (MZ)

Abant Izzet Baysal University Hospital, Department of Internal Medicine, Bolu, Turkey.

Haluk Savli (H)

Abant Izzet Baysal University Hospital, Department of Internal Medicine, Bolu, Turkey.

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Classifications MeSH