Association Between Patient and Physician Sex and Physician-Estimated Stroke and Bleeding Risks in Atrial Fibrillation.


Journal

The Canadian journal of cardiology
ISSN: 1916-7075
Titre abrégé: Can J Cardiol
Pays: England
ID NLM: 8510280

Informations de publication

Date de publication:
02 2019
Historique:
received: 23 07 2018
revised: 27 11 2018
accepted: 28 11 2018
entrez: 15 2 2019
pubmed: 15 2 2019
medline: 19 11 2019
Statut: ppublish

Résumé

Physicians treating nonvalvular atrial fibrillation (AF) assess stroke and bleeding risks when deciding on anticoagulation. The agreement between empirical and physician-estimated risks is unclear. Furthermore, the association between patient and physician sex and anticoagulation decision-making is uncertain. We pooled data from 2 national primary care physician chart audit databases of patients with AF (Facilitating Review and Education to Optimize Stroke Prevention in Atrial Fibrillation and Coordinated National Network to Engage Physicians in the Care and Treatment of Patients with Atrial Fibrillation Chart Audit) with a combined 1035 physicians (133 female, 902 male) and 10,927 patients (4567 female and 6360 male). Male physicians underestimated stroke risk in female patients and overestimated risk in male patients. Female physicians estimated stroke risk well in female patients but underestimated the risk in male patients. Risk of bleeding was underestimated in all. Despite differences in risk assessment by physician and patient sex, > 90% of patients received anticoagulation across all subgroups. There was modest agreement between physician estimated and calculated (ie, CHADS Our study is the first to examine the association between patient and physician sex influences and stroke and bleeding risk estimation in AF. Although there were differences in agreement between physician estimated stroke risk and calculated CHADS

Sections du résumé

BACKGROUND
Physicians treating nonvalvular atrial fibrillation (AF) assess stroke and bleeding risks when deciding on anticoagulation. The agreement between empirical and physician-estimated risks is unclear. Furthermore, the association between patient and physician sex and anticoagulation decision-making is uncertain.
METHODS
We pooled data from 2 national primary care physician chart audit databases of patients with AF (Facilitating Review and Education to Optimize Stroke Prevention in Atrial Fibrillation and Coordinated National Network to Engage Physicians in the Care and Treatment of Patients with Atrial Fibrillation Chart Audit) with a combined 1035 physicians (133 female, 902 male) and 10,927 patients (4567 female and 6360 male).
RESULTS
Male physicians underestimated stroke risk in female patients and overestimated risk in male patients. Female physicians estimated stroke risk well in female patients but underestimated the risk in male patients. Risk of bleeding was underestimated in all. Despite differences in risk assessment by physician and patient sex, > 90% of patients received anticoagulation across all subgroups. There was modest agreement between physician estimated and calculated (ie, CHADS
CONCLUSIONS
Our study is the first to examine the association between patient and physician sex influences and stroke and bleeding risk estimation in AF. Although there were differences in agreement between physician estimated stroke risk and calculated CHADS

Identifiants

pubmed: 30760422
pii: S0828-282X(18)31313-8
doi: 10.1016/j.cjca.2018.11.023
pii:
doi:

Substances chimiques

Anticoagulants 0

Types de publication

Journal Article Multicenter Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

160-168

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2018 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.

Auteurs

Hanna Lee (H)

Terrence Donnelly Heart Centre, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.

Mary K Tan (MK)

Canadian Heart Research Centre, Toronto, Ontario, Canada.

Andrew T Yan (AT)

Terrence Donnelly Heart Centre, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.

Paul Angaran (P)

Terrence Donnelly Heart Centre, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.

Paul Dorian (P)

Terrence Donnelly Heart Centre, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.

Claudia Bucci (C)

Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

Jean C Gregoire (JC)

Université de Montréal, Institut de Cardiologie de Montréal, Montréal, Quebec, Canada.

Alan D Bell (AD)

University of Toronto, Department of Family and Community Medicine, Toronto, Ontario, Canada.

Martin S Green (MS)

University of Ottawa Heart Institute, Ottawa, Ontario, Canada.

Peter L Gross (PL)

Thrombosis and Atherosclerosis Research Institute, McMaster University, Juravinski Henderson Hospital, Hamilton, Ontario, Canada.

Allan Skanes (A)

Western University, London, Ontario, Canada.

Charles R Kerr (CR)

St Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.

L Brent Mitchell (LB)

Department of Cardiac Sciences, Libin Cardiovascular Institute of Alberta, University of Calgary and Alberta Health Services, Calgary, Alberta, Canada.

Jafna L Cox (JL)

Dalhousie University, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia.

Vidal Essebag (V)

McGill University Health Centre and Hôpital Sacré Coeur de Montréal, Montréal, Quebec, Canada.

Brett Heilbron (B)

St Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.

Krishnan Ramanathan (K)

St Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.

Carl Fournier (C)

Hôpital Notre-Dame, Université de Montréal, Montreal, Quebec, Canada.

Bruce H Wheeler (BH)

Calgary Foothills Primary Care Network, Calgary, Alberta, Canada.

Peter J Lin (PJ)

Canadian Heart Research Centre, Toronto, Ontario, Canada.

Murray Berall (M)

University of Toronto, Department of Family and Community Medicine, Toronto, Ontario, Canada; Humber River Hospital, Toronto, Ontario, Canada.

Anatoly Langer (A)

Canadian Heart Research Centre, Toronto, Ontario, Canada.

Lianne Goldin (L)

Canadian Heart Research Centre, Toronto, Ontario, Canada.

Shaun G Goodman (SG)

Terrence Donnelly Heart Centre, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada; Canadian Heart Research Centre, Toronto, Ontario, Canada. Electronic address: goodmans@chrc.net.

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Classifications MeSH