Health Care Utilization After Ventricular Tachycardia Ablation: A Propensity Score-Matched Cohort Study.


Journal

The Canadian journal of cardiology
ISSN: 1916-7075
Titre abrégé: Can J Cardiol
Pays: England
ID NLM: 8510280

Informations de publication

Date de publication:
02 2019
Historique:
received: 17 07 2018
revised: 10 10 2018
accepted: 15 10 2018
entrez: 15 2 2019
pubmed: 15 2 2019
medline: 19 11 2019
Statut: ppublish

Résumé

Catheter ablation of ventricular tachycardia (VT) can reduce the burden of ventricular arrhythmia (VA) but its effect on health care utilization and costs after such therapy is poorly known. We sought to compare the rates of cardiovascular (CV)-related hospitalizations, survival, and health care costs in patients with recurrent VT treated either with VT ablation or with medical therapy. One-hundred implantable cardioverter-defibrillator patients with structural heart disease who underwent VT ablation were included. Propensity score-matched patients with recurrent VT treated with medical therapy were identified from a prospective registry of approximately 7000 de novo implantable cardioverter-defibrillator patients. Outcomes and costs were ascertained using health administrative databases. Among patients who underwent VT ablation, the cumulative rates of VA-related hospitalizations were lower in the 2 years after their ablation procedure compared with the year before (rate ratio, 0.3; 95% confidence interval [CI], 0.22-0.43). Rates of CV-related hospitalization and hospitalization because of VA post index date were similar between the VT ablation and medical therapy groups (hazard ratio [HR], 0.94; 95% CI, 0.57-1.54 and HR, 1.04; 95% CI, 0.57-1.91, respectively). Health care costs in the VT ablation patients were not increased post-ablation compared with the medical management group. The risk of all-cause mortality was lower among patients in the VT ablation group relative to the medical therapy group (HR, 0.64; 95% CI, 0.4-0.99). Patients who underwent VT ablation experienced a significant reduction in their rate of VA-related hospitalizations. Patients treated with VT ablation had similar rates of CV-related hospitalization compared with those treated with medical therapy without increased health care-related costs.

Sections du résumé

BACKGROUND
Catheter ablation of ventricular tachycardia (VT) can reduce the burden of ventricular arrhythmia (VA) but its effect on health care utilization and costs after such therapy is poorly known. We sought to compare the rates of cardiovascular (CV)-related hospitalizations, survival, and health care costs in patients with recurrent VT treated either with VT ablation or with medical therapy.
METHODS
One-hundred implantable cardioverter-defibrillator patients with structural heart disease who underwent VT ablation were included. Propensity score-matched patients with recurrent VT treated with medical therapy were identified from a prospective registry of approximately 7000 de novo implantable cardioverter-defibrillator patients. Outcomes and costs were ascertained using health administrative databases.
RESULTS
Among patients who underwent VT ablation, the cumulative rates of VA-related hospitalizations were lower in the 2 years after their ablation procedure compared with the year before (rate ratio, 0.3; 95% confidence interval [CI], 0.22-0.43). Rates of CV-related hospitalization and hospitalization because of VA post index date were similar between the VT ablation and medical therapy groups (hazard ratio [HR], 0.94; 95% CI, 0.57-1.54 and HR, 1.04; 95% CI, 0.57-1.91, respectively). Health care costs in the VT ablation patients were not increased post-ablation compared with the medical management group. The risk of all-cause mortality was lower among patients in the VT ablation group relative to the medical therapy group (HR, 0.64; 95% CI, 0.4-0.99).
CONCLUSIONS
Patients who underwent VT ablation experienced a significant reduction in their rate of VA-related hospitalizations. Patients treated with VT ablation had similar rates of CV-related hospitalization compared with those treated with medical therapy without increased health care-related costs.

Identifiants

pubmed: 30760423
pii: S0828-282X(18)31229-7
doi: 10.1016/j.cjca.2018.10.011
pii:
doi:

Substances chimiques

Anti-Arrhythmia Agents 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

169-177

Subventions

Organisme : CIHR
ID : MOP 111150
Pays : Canada
Organisme : CIHR
ID : FDN 148446
Pays : Canada

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2018 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.

Auteurs

Andreu Porta-Sánchez (A)

University Health Network, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada; Departament de Medicina, Universitat de Barcelona and Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.

Andrew C T Ha (ACT)

University Health Network, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.

Xuesong Wang (X)

Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.

Fahad Almehmadi (F)

University Health Network, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.

Peter C Austin (PC)

Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.

Hadas D Fischer (HD)

Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.

Atif Al-Qubbany (A)

University Health Network, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.

Diego Chemello (D)

University Health Network, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.

Vijay Chauhan (V)

University Health Network, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.

Eugene Downar (E)

University Health Network, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.

Douglas S Lee (DS)

University Health Network, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada; Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada. Electronic address: dlee@ices.on.ca.

Kumaraswamy Nanthakumar (K)

University Health Network, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada. Electronic address: Kumar.Nanthakumar@uhn.ca.

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