Ambient and controlled exposures to particulate air pollution and acute changes in heart rate variability and repolarization.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
13 02 2019
Historique:
received: 18 09 2018
accepted: 27 12 2018
entrez: 15 2 2019
pubmed: 15 2 2019
medline: 26 8 2020
Statut: epublish

Résumé

Previous studies have reported increased risks of myocardial infarction in association with elevated ambient particulate matter (PM) in the previous hour(s). However, whether PM can trigger mechanisms that act on this time scale is still unclear. We hypothesized that increases in PM are associated with rapid changes in measures of heart rate variability and repolarization. We used data from panel studies in Augsburg, Germany, and Rochester, New York, USA, and two controlled human exposure studies in Rochester. Data included ECG recordings from all four studies, controlled exposures to (concentrated) ultrafine particles (UFP; particles with an aerodynamic diameter <100 nm) and ambient concentrations of UFP and fine PM (PM

Identifiants

pubmed: 30760868
doi: 10.1038/s41598-019-38531-9
pii: 10.1038/s41598-019-38531-9
pmc: PMC6374365
doi:

Substances chimiques

Air Pollutants 0
Particulate Matter 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1946

Subventions

Organisme : NIEHS NIH HHS
ID : T32 ES007271
Pays : United States

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Auteurs

Susanne Breitner (S)

Helmholtz Zentrum München-German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany. susanne.breitner@helmholtz-muenchen.de.
Ludwig-Maximilians-Universität München, IBE-Chair of Epidemiology, Munich, Germany. susanne.breitner@helmholtz-muenchen.de.

Annette Peters (A)

Helmholtz Zentrum München-German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany.
Ludwig-Maximilians-Universität München, IBE-Chair of Epidemiology, Munich, Germany.

Wojciech Zareba (W)

University of Rochester Medical Center, Rochester, New York, USA.

Regina Hampel (R)

Helmholtz Zentrum München-German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany.

David Oakes (D)

University of Rochester Medical Center, Rochester, New York, USA.

Jelani Wiltshire (J)

University of Rochester Medical Center, Rochester, New York, USA.

Mark W Frampton (MW)

University of Rochester Medical Center, Rochester, New York, USA.

Philip K Hopke (PK)

Clarkson University, Potsdam, New York, USA.

Josef Cyrys (J)

Helmholtz Zentrum München-German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany.

Mark J Utell (MJ)

University of Rochester Medical Center, Rochester, New York, USA.

Cathleen Kane (C)

University of Rochester Medical Center, Rochester, New York, USA.

Alexandra Schneider (A)

Helmholtz Zentrum München-German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany.

David Q Rich (DQ)

University of Rochester Medical Center, Rochester, New York, USA.

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Classifications MeSH