Laparoscopic cytoreductive surgery and HIPEC is effective regarding peritoneum tissue paclitaxel distribution.
Animals
Antineoplastic Agents, Phytogenic
/ administration & dosage
Chemotherapy, Cancer, Regional Perfusion
Combined Modality Therapy
Cytoreduction Surgical Procedures
/ methods
Female
Hyperthermia, Induced
Laparoscopy
/ methods
Lymph Node Excision
/ methods
Paclitaxel
/ administration & dosage
Pelvic Neoplasms
/ metabolism
Peritoneal Neoplasms
/ metabolism
Swine
Tissue Distribution
HIPEC
Hyperthermic intra-abdominal chemotherapy
Laparoscopy
Paclitaxel
Peritoneum paclitaxel distribution
Journal
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
ISSN: 1699-3055
Titre abrégé: Clin Transl Oncol
Pays: Italy
ID NLM: 101247119
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
24
09
2018
accepted:
25
01
2019
pubmed:
15
2
2019
medline:
7
1
2020
entrez:
15
2
2019
Statut:
ppublish
Résumé
In some patients with peritoneal carcinomatosis, we could perform the cytoreductive surgery and the HIPEC procedure by a complete laparoscopic approach to avoid morbidity. We consider that using laparoscopic approach for performing peritoneal carcinomatosis cytoreductive surgery and HIPEC with closed CO Monitoring the effectiveness of the drug distribution in a laparoscopic ctoreductive and HIPEC surgery group with CO G1-G2: phrenic right peritoneum, p: 0.46. Phrenic left peritoneum, p: 0.46. Pelvic peritoneum, p: 0.17. Serum paclitaxel: p: 0.01. G1-G3: phrenic right peritoneum, p: 0.34. Phrenic left peritoneum, p: 0.34. Pelvic peritoneum, p: 0.17. Serum paclitaxel G1-G3, p: 0.02. A total laparoscopic approach for ctoreductive surgery and closed HIPEC with CO
Sections du résumé
BACKGROUND
BACKGROUND
In some patients with peritoneal carcinomatosis, we could perform the cytoreductive surgery and the HIPEC procedure by a complete laparoscopic approach to avoid morbidity. We consider that using laparoscopic approach for performing peritoneal carcinomatosis cytoreductive surgery and HIPEC with closed CO
OBJECTIVE
OBJECTIVE
Monitoring the effectiveness of the drug distribution in a laparoscopic ctoreductive and HIPEC surgery group with CO
RESULTS
RESULTS
G1-G2: phrenic right peritoneum, p: 0.46. Phrenic left peritoneum, p: 0.46. Pelvic peritoneum, p: 0.17. Serum paclitaxel: p: 0.01. G1-G3: phrenic right peritoneum, p: 0.34. Phrenic left peritoneum, p: 0.34. Pelvic peritoneum, p: 0.17. Serum paclitaxel G1-G3, p: 0.02.
CONCLUSIONS
CONCLUSIONS
A total laparoscopic approach for ctoreductive surgery and closed HIPEC with CO
Identifiants
pubmed: 30761508
doi: 10.1007/s12094-019-02052-8
pii: 10.1007/s12094-019-02052-8
doi:
Substances chimiques
Antineoplastic Agents, Phytogenic
0
Paclitaxel
P88XT4IS4D
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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