New organoruthenium compounds with pyrido[2',3':5,6]pyrazino[2,3-f][1, 10]phenanthroline: synthesis, characterization, cytotoxicity, and investigation of mechanism of action.
Antineoplastic Agents
/ chemical synthesis
Cell Cycle
/ drug effects
Cell Proliferation
/ drug effects
Coordination Complexes
/ chemical synthesis
Dose-Response Relationship, Drug
Drug Screening Assays, Antitumor
Humans
Molecular Structure
Phenanthrolines
/ chemistry
Ruthenium
/ chemistry
Structure-Activity Relationship
Tumor Cells, Cultured
Anticancer agents
Biological activity
DNA intercalating ligand
Ruthenium(II)–arene complexes
Journal
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry
ISSN: 1432-1327
Titre abrégé: J Biol Inorg Chem
Pays: Germany
ID NLM: 9616326
Informations de publication
Date de publication:
03 2019
03 2019
Historique:
received:
06
12
2018
accepted:
28
01
2019
pubmed:
15
2
2019
medline:
29
2
2020
entrez:
15
2
2019
Statut:
ppublish
Résumé
Three new ruthenium(II)-arene complexes with pyrido[2',3':5,6]pyrazino[2,3-f][1, 10]phenanthroline (ppf) of general formula: C1 ([(ƞ
Identifiants
pubmed: 30762123
doi: 10.1007/s00775-019-01647-4
pii: 10.1007/s00775-019-01647-4
doi:
Substances chimiques
Antineoplastic Agents
0
Coordination Complexes
0
Phenanthrolines
0
Ruthenium
7UI0TKC3U5
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
297-310Références
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