Abnormal Fractional Flow Reserve in Nonobstructive Coronary Artery Disease.
Adenosine Triphosphate
/ administration & dosage
Aged
Aged, 80 and over
Computed Tomography Angiography
Coronary Angiography
/ methods
Coronary Artery Disease
/ diagnostic imaging
Coronary Vessels
/ diagnostic imaging
Female
Fractional Flow Reserve, Myocardial
Humans
Infusions, Intravenous
Male
Middle Aged
Predictive Value of Tests
Prognosis
Retrospective Studies
Vasodilator Agents
/ administration & dosage
angiography
atherosclerotic plaque
coronary artery disease
coronary computed tomography angiography
fractional flow reserve
Journal
Circulation. Cardiovascular interventions
ISSN: 1941-7632
Titre abrégé: Circ Cardiovasc Interv
Pays: United States
ID NLM: 101499602
Informations de publication
Date de publication:
02 2019
02 2019
Historique:
entrez:
16
2
2019
pubmed:
16
2
2019
medline:
26
2
2020
Statut:
ppublish
Résumé
Background The basis of discordance between invasive coronary angiographic (ICA) anatomic stenosis and fractional flow reserve (FFR) is not fully understood. We analyzed coronary computed tomography angiography (CTA) characteristics of ICA-verified nonobstructive lesions in the proximal or midleft anterior descending artery with FFR ≤0.8, that is, anatomy-physiology mismatch. Methods and Results CTA and ICA were performed in 108 patients. FFR was measured during intravenous ATP (180 μg/[kg·min]) infusion. CTA-verified plaque characteristics between 53 consecutive ICA-FFR mismatch (ICA-quantitative coronary angiography <50%, FFR≤0.8) and 55 ICA-FFR match (ICA-quantitative coronary angiography<50%, FFR>0.8) vessels were compared. CTA-verified vessel area (20.7±6.7 versus 16.9±4.8 mm
Identifiants
pubmed: 30767658
doi: 10.1161/CIRCINTERVENTIONS.118.006961
doi:
Substances chimiques
Vasodilator Agents
0
Adenosine Triphosphate
8L70Q75FXE
Types de publication
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM