Clinical Features and Multi-Modality Imaging of Isolated Retinal Astrocytic Hamartoma.
Adult
Aged, 80 and over
Astrocytes
/ pathology
Child
Diagnostic Techniques, Ophthalmological
Female
Fluorescein Angiography
/ methods
Fundus Oculi
Hamartoma
/ diagnostic imaging
Humans
Male
Middle Aged
Multimodal Imaging
/ methods
Optical Imaging
/ methods
Retinal Neoplasms
/ diagnostic imaging
Sensitivity and Specificity
Ultrasonography
Young Adult
Journal
Ophthalmic surgery, lasers & imaging retina
ISSN: 2325-8179
Titre abrégé: Ophthalmic Surg Lasers Imaging Retina
Pays: United States
ID NLM: 101599215
Informations de publication
Date de publication:
01 02 2019
01 02 2019
Historique:
received:
22
03
2018
accepted:
04
05
2018
entrez:
16
2
2019
pubmed:
16
2
2019
medline:
9
4
2019
Statut:
ppublish
Résumé
To identify the clinical and imaging characteristics of isolated retinal astrocytic hamartomas (IRAH). A case series of eight patients diagnosed with IRAH. The average age at diagnosis was 32 years (range: 9 years to 80 years). After a median follow-up time of 59 months, none of the lesions had demonstrated any change or growth. Fundus fluorescein angiogram identified hyperfluorescence in five of six imaged lesions. Fundus autofluorescence (FAF) changes were seen in all eight cases. Ocular ultrasound was able to identify a lesion in only five of the seven cases. Optical coherence tomography (OCT) was able to document the tumor thickness and level of retinal invasion in all cases. Multimodal imaging is useful for the diagnosis and monitoring of IRAH. OCT and FAF are sensitivity tools for identifying IRA and can be used to follow the thickness and margins of these lesions. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:e1-e9.].
Sections du résumé
BACKGROUND AND OBJECTIVE
To identify the clinical and imaging characteristics of isolated retinal astrocytic hamartomas (IRAH).
PATIENTS AND METHODS
A case series of eight patients diagnosed with IRAH.
RESULTS
The average age at diagnosis was 32 years (range: 9 years to 80 years). After a median follow-up time of 59 months, none of the lesions had demonstrated any change or growth. Fundus fluorescein angiogram identified hyperfluorescence in five of six imaged lesions. Fundus autofluorescence (FAF) changes were seen in all eight cases. Ocular ultrasound was able to identify a lesion in only five of the seven cases. Optical coherence tomography (OCT) was able to document the tumor thickness and level of retinal invasion in all cases.
CONCLUSIONS
Multimodal imaging is useful for the diagnosis and monitoring of IRAH. OCT and FAF are sensitivity tools for identifying IRA and can be used to follow the thickness and margins of these lesions. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:e1-e9.].
Identifiants
pubmed: 30768223
doi: 10.3928/23258160-20190129-12
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e1-e9Informations de copyright
Copyright 2019, SLACK Incorporated.