Adolescent Victimization and Self-Injurious Thoughts and Behaviors: A Genetically Sensitive Cohort Study.


Journal

Journal of the American Academy of Child and Adolescent Psychiatry
ISSN: 1527-5418
Titre abrégé: J Am Acad Child Adolesc Psychiatry
Pays: United States
ID NLM: 8704565

Informations de publication

Date de publication:
05 2019
Historique:
received: 12 04 2018
revised: 07 06 2018
accepted: 15 08 2018
pubmed: 16 2 2019
medline: 12 5 2020
entrez: 16 2 2019
Statut: ppublish

Résumé

Victimized adolescents have an increased risk of self-injurious thoughts and behaviors. However, poor understanding of causal and non-causal mechanisms underlying this observed risk limits the development of interventions to prevent premature death in adolescents. This study tested whether pre-existing family-wide and individual vulnerabilities account for victimized adolescents' increased risk of self-injurious thoughts and behaviors. Participants were 2,232 British children followed from birth to 18 years of age as part of the Environmental Risk Longitudinal Twin Study. Adolescent victimization (maltreatment, neglect, sexual victimization, family violence, peer/sibling victimization, cyber victimization, and crime victimization) was assessed through interviews with participants and co-informant questionnaires at the 18-year assessment. Suicidal ideation, self-harm, and suicide attempt in adolescence were assessed through interviews with participants at 18 years. Victimized adolescents had an increased risk of suicidal ideation (odds ratio [OR] 2.40, 95% CI 2.11-2.74), self-harm (OR 2.38, 95% CI 2.10-2.69), and suicide attempt (OR 3.14, 95% CI 2.54-3.88). Co-twin control and propensity score matching analyses showed that these associations were largely accounted for by pre-existing familial and individual vulnerabilities, respectively. Over and above their prior vulnerabilities, victimized adolescents still showed a modest increase in risk for suicidal ideation (OR 1.45, 95%CI 1.10-1.91) and self-harm (OR 1.50, 95% CI 1.18-1.91) but not for suicide attempt (OR 1.28, 95% CI 0.83-1.98). Risk for self-injurious thoughts and behaviors in victimized adolescents is explained only in part by the experience of victimization. Pre-existing vulnerabilities account for a large proportion of the risk. Therefore, effective interventions to prevent premature death in victimized adolescents should not only target the experience of victimization but also address pre-existing vulnerabilities.

Identifiants

pubmed: 30768402
pii: S0890-8567(18)32033-1
doi: 10.1016/j.jaac.2018.07.903
pmc: PMC6494951
pii:
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Twin Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

506-513

Subventions

Organisme : Medical Research Council
ID : G1002190
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/P005918/1
Pays : United Kingdom
Organisme : NICHD NIH HHS
ID : P2C HD065563
Pays : United States
Organisme : NICHD NIH HHS
ID : R01 HD077482
Pays : United States

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

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Auteurs

Jessie R Baldwin (JR)

King's College London, UK.

Louise Arseneault (L)

King's College London, UK.

Avshalom Caspi (A)

King's College London, UK; Duke University.

Terrie E Moffitt (TE)

King's College London, UK; Duke University.

Helen L Fisher (HL)

King's College London, UK.

Candice L Odgers (CL)

Duke University, Durham, NC; University of California, Irvine.

Antony Ambler (A)

King's College London, UK.

Renate M Houts (RM)

Duke University, Durham, NC.

Timothy Matthews (T)

King's College London, UK.

Leah S Richmond-Rakerd (LS)

Duke University, Durham, NC.

Ryu Takizawa (R)

Graduate School of Education, The University of Tokyo, Japan.

Andrea Danese (A)

King's College London, UK; National and Specialist CAMHS Clinic for Trauma, Anxiety, and Depression, South London and the Maudsley NHS Foundation Trust, London, UK. Electronic address: andrea.danese@kcl.ac.uk.

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Classifications MeSH