Centrifugal-flow ventricular assist device support in children: A single-center experience.


Journal

The Journal of thoracic and cardiovascular surgery
ISSN: 1097-685X
Titre abrégé: J Thorac Cardiovasc Surg
Pays: United States
ID NLM: 0376343

Informations de publication

Date de publication:
04 2019
Historique:
received: 18 05 2018
revised: 28 11 2018
accepted: 13 12 2018
pubmed: 17 2 2019
medline: 25 2 2020
entrez: 17 2 2019
Statut: ppublish

Résumé

Our institutional policy is to continue centrifugal-flow ventricular assist device support for 3 months or more without activation on the transplant wait-list for physical recovery and assessment of possible myocardial recovery. We evaluated our single-institutional outcomes with centrifugal-flow ventricular assist device support in children. Prospectively collected outcomes data in consecutive patients aged 18 years or less with centrifugal-flow ventricular assist device support were reviewed. There were 40 implantations in 39 patients (28 with cardiomyopathy, 11 with congenital heart disease, including 3 with univentricular physiology). The median support was 8 months (range, 1-79), with 13 patients (33%) supported for 12 months or more and a cumulative duration of 41 patient-years. The median age and weight at implantation were 11 (4-18) years and 35 (14-98) kg, respectively. The median body surface area was 1.1 (0.7-2.2) m This study demonstrates favorable outcomes of centrifugal-flow ventricular assist device support in children, including those with congenital heart disease, with an increased incidence of cardiac recovery.

Sections du résumé

BACKGROUND
Our institutional policy is to continue centrifugal-flow ventricular assist device support for 3 months or more without activation on the transplant wait-list for physical recovery and assessment of possible myocardial recovery. We evaluated our single-institutional outcomes with centrifugal-flow ventricular assist device support in children.
METHODS
Prospectively collected outcomes data in consecutive patients aged 18 years or less with centrifugal-flow ventricular assist device support were reviewed.
RESULTS
There were 40 implantations in 39 patients (28 with cardiomyopathy, 11 with congenital heart disease, including 3 with univentricular physiology). The median support was 8 months (range, 1-79), with 13 patients (33%) supported for 12 months or more and a cumulative duration of 41 patient-years. The median age and weight at implantation were 11 (4-18) years and 35 (14-98) kg, respectively. The median body surface area was 1.1 (0.7-2.2) m
CONCLUSIONS
This study demonstrates favorable outcomes of centrifugal-flow ventricular assist device support in children, including those with congenital heart disease, with an increased incidence of cardiac recovery.

Identifiants

pubmed: 30770106
pii: S0022-5223(18)33484-6
doi: 10.1016/j.jtcvs.2018.12.045
pii:
doi:

Types de publication

Journal Article Video-Audio Media

Langues

eng

Sous-ensembles de citation

IM

Pagination

1609-1617.e2

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2018 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.

Auteurs

Iki Adachi (I)

Congenital Heart Surgery, Texas Children's Hospital, Baylor College of Medicine, Houston, Tex. Electronic address: iadachi@bcm.edu.

Rodrigo Zea-Vera (R)

Congenital Heart Surgery, Texas Children's Hospital, Baylor College of Medicine, Houston, Tex.

Hari Tunuguntla (H)

Pediatric Cardiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Tex.

Susan W Denfield (SW)

Pediatric Cardiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Tex.

Barbara Elias (B)

Congenital Heart Surgery, Texas Children's Hospital, Baylor College of Medicine, Houston, Tex.

Rija John (R)

Congenital Heart Surgery, Texas Children's Hospital, Baylor College of Medicine, Houston, Tex.

Jun Teruya (J)

Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, Tex.

Charles D Fraser (CD)

Congenital Heart Surgery, Texas Children's Hospital, Baylor College of Medicine, Houston, Tex.

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