Challenges in Advancing Necrotizing Enterocolitis Research.
Clinical trials
Necrotizing enterocolitis
Preclinical research
Journal
Clinics in perinatology
ISSN: 1557-9840
Titre abrégé: Clin Perinatol
Pays: United States
ID NLM: 7501306
Informations de publication
Date de publication:
03 2019
03 2019
Historique:
entrez:
18
2
2019
pubmed:
18
2
2019
medline:
19
6
2019
Statut:
ppublish
Résumé
Progressing necrotizing enterocolitis research is difficult because the disease is variable in presentation, there are difficulties in making a precise diagnosis, a reliable agreed case-definition is currently lacking, and there is a paucity of preclinical research to identify etiologic targets. The major challenges of the cost of clinical trials and need for long-term outcome ascertainment could be eased through incorporation of novel randomization approaches and data collection into routine care, and collaboration between public-sector and industry funders.
Identifiants
pubmed: 30771816
pii: S0095-5108(18)31431-3
doi: 10.1016/j.clp.2018.10.002
pii:
doi:
Substances chimiques
Biomarkers
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
19-27Subventions
Organisme : Department of Health
ID : RP-PG-0707-10010
Pays : United Kingdom
Informations de copyright
Copyright © 2018 Elsevier Inc. All rights reserved.