Acute Respiratory Illness in Rural Haiti.
Acute Disease
/ epidemiology
Adolescent
Adult
Child
Child, Preschool
Female
Haiti
/ epidemiology
Humans
Infant
Male
Real-Time Polymerase Chain Reaction
Respiratory Tract Infections
/ epidemiology
Retrospective Studies
Rural Population
/ statistics & numerical data
Staphylococcal Infections
/ epidemiology
Staphylococcus aureus
/ classification
Streptococcus pneumoniae
/ genetics
Virus Diseases
/ epidemiology
Viruses
/ classification
Young Adult
Acute Respiratory Illness (ARI)
Children
Haiti
Outpatient
Rural
Journal
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
ISSN: 1878-3511
Titre abrégé: Int J Infect Dis
Pays: Canada
ID NLM: 9610933
Informations de publication
Date de publication:
Apr 2019
Apr 2019
Historique:
received:
27
11
2018
revised:
01
02
2019
accepted:
08
02
2019
pubmed:
18
2
2019
medline:
28
8
2019
entrez:
18
2
2019
Statut:
ppublish
Résumé
Acute Respiratory Infection (ARI) is the most common cause of childhood morbidity and mortality in developing countries, including Haiti. Our objective was to detect pathogens found in children with ARI in rural Haiti to help develop evidence-based guidelines for treatment and prevention. Retrospective study of students with ARI at four schools in rural Haiti. Viral and/or bacterial pathogens were identified by qPCR in 177 nasal swabs collected from April 2013 through November 2015. Most common viruses detected were Rhinovirus (36%), Influenza A (16%) and Adenovirus (7%), and bacteria were Streptococcus pneumoniae (58%) and Staphylococcus aureus (28%). Compared to older children, children aged 3-5 years had more Influenza A (28% vs. 9%, p=0.002) and Adenovirus detected (14% vs. 3%, p=0.01). Similarly, S. pneumoniae was greatest in children 3-5 years old (71% 3-5yrs; 58% 6-15 years; 25% 16-20 years; p=0.008). Children 3-10 years old presented with fever more than children 11-20 years old (22% vs 7%; p=0.02) and were more often diagnosed with pneumonia (28% vs 4%, p<0.001). Younger children had increased fever, pneumonia, and detection of Influenza A and S. pneumoniae. These data support the need for influenza and pneumococcus vaccination in early childhood in Haiti.
Identifiants
pubmed: 30772468
pii: S1201-9712(19)30067-0
doi: 10.1016/j.ijid.2019.02.003
pmc: PMC7173118
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
176-183Subventions
Organisme : NIAID NIH HHS
ID : R01 AI126357
Pays : United States
Informations de copyright
Copyright © 2019 The Authors. Published by Elsevier Ltd.. All rights reserved.
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