Behavioural alterations induced by the anxiolytic pollutant oxazepam are reversible after depuration in a freshwater fish.

Animals Anti-Anxiety Agents / adverse effects Behavior, Animal / drug effects Dose-Response Relationship, Drug Feeding Behavior / drug effects Gadiformes / metabolism Oxazepam / adverse effects Random Allocation Swimming Water Pollutants, Chemical / adverse effects
Benzodiazepines Boldness Pharmaceutical contaminants Swimming activity

Journal

The Science of the total environment
ISSN: 1879-1026
Titre abrégé: Sci Total Environ
Pays: Netherlands
ID NLM: 0330500

Informations de publication

Date de publication:
15 May 2019
Historique:
received: 27 11 2018
revised: 29 01 2019
accepted: 03 02 2019
pubmed: 18 2 2019
medline: 9 4 2019
entrez: 18 2 2019
Statut: ppublish

Résumé

Anthropogenic pharmaceutical pollutants have been detected in nature across the globe, and recent work has shown negative effects of pharmaceuticals on the health and welfare of many animals. However, whether alterations can be reversed has been poorly investigated, although such studies are essential to assess the effects of high-peak exposure events in waterways where pharmaceutical concentrations are usually low. In this study, we investigated the effects of two concentrations (environmentally relevant 1 μg L

Identifiants

DOI: 10.1016/j.scitotenv.2019.02.049 PMID: 30772569
pubmed: 30772569
pii: S0048-9697(19)30528-5
doi: 10.1016/j.scitotenv.2019.02.049
pii:
doi:

Substances chimiques

Anti-Anxiety Agents 0
Water Pollutants, Chemical 0
Oxazepam 6GOW6DWN2A

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

390-399

Informations de copyright

Copyright © 2019 Elsevier B.V. All rights reserved.

Auteurs

Josefin Sundin (J)

Department of Neuroscience, Uppsala University, 75124 Uppsala, Sweden. Electronic address: josefin@teamsundin.se.

Fredrik Jutfelt (F)

Department of Biology, Norwegian University of Science and Technology, 7491 Trondheim, Norway. Electronic address: fredrik.jutfelt@ntnu.no.

Magnús Thorlacius (M)

Marine and Freshwater Research Institute, 101 Reykjavik, Iceland. Electronic address: magnus.thorlacius@hafogvatn.is.

Jerker Fick (J)

Department of Chemistry, Umeå University, 90187 Umeå, Sweden. Electronic address: jerker.fick@umu.se.

Tomas Brodin (T)

Department of Ecology and Environmental Science, Umeå University, 90187 Umeå, Sweden. Electronic address: tomas.brodin@slu.se.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Behavioural alterations induced by the...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents du système nerveux central › Psychoanaleptiques › Tranquillisants › Anxiolytiques › Behavioural alterations induced by the...
questionsmedicales.fr › Comportement et mécanismes comportementaux › Comportement › Comportement animal › Behavioural alterations induced by the...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes toxicologiques › Relation dose-effet des médicaments › Behavioural alterations induced by the...
questionsmedicales.fr › Phénomènes physiologiques › Alimentation et nutrition › Phénomènes physiologiques nutritionnels › Comportement alimentaire › Behavioural alterations induced by the...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Poissons › Gadiformes › Behavioural alterations induced by the...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Benzazépines › Benzodiazépines › Benzodiazépinones › Oxazépam › Behavioural alterations induced by the...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Méthodologie en recherche épidémiologique › Répartition aléatoire › Behavioural alterations induced by the...
questionsmedicales.fr › Activités humaines › Activités de loisirs › Loisir › Sports › Sports nautiques › Natation › Behavioural alterations induced by the...
questionsmedicales.fr › Actions chimiques et utilisations › Actions toxiques › Polluants environnementaux › Polluants de l'eau › Polluants chimiques de l'eau › Behavioural alterations induced by the...