Minimal clinically important difference of 3-minute chair rise test and the DIRECT questionnaire after pulmonary rehabilitation in COPD patients.


Journal

International journal of chronic obstructive pulmonary disease
ISSN: 1178-2005
Titre abrégé: Int J Chron Obstruct Pulmon Dis
Pays: New Zealand
ID NLM: 101273481

Informations de publication

Date de publication:
Historique:
entrez: 19 2 2019
pubmed: 19 2 2019
medline: 30 7 2019
Statut: epublish

Résumé

The 3-minute chair rise test (3-minute CRT) and the Disability Related to COPD Tool (DIRECT) are two reproducible and valid short tests that can assess the benefit of pulmonary rehabilitation (PR) in terms of functional capacity and dyspnea in everyday activities. We determined the minimal clinically important difference (MCID) of the DIRECT questionnaire and 3-minute CRT using distribution methods and anchor encroaches with a panel of eight standard tests in a cohort of 116 COPD patients who completed a PR program in real-life settings. The estimated MCID for the 3-minute CRT and DIRECT scores was five repetitions and two units, respectively, using separate and combined independent anchors. The all-patient (body mass index-obstruction-dyspnea-exercise [BODE] scores 0-7), BODE 0-2 (n=42), and BODE 3-4 (n=50) groups showed improvements greater than the MCID in most tests and questionnaires used. In contrast, the BODE 5-7 group (n=24) showed improvements greater than MCID in only the 3-minute CRT, 6-minute walk test, endurance exercise test, and DIRECT questionnaire. This study demonstrates that the short and simple DIRECT questionnaire and 3-minute CRT are responsive to capture the beneficial effects of a PR program in COPD patients, including those with severe disease. NCT03286660.

Sections du résumé

BACKGROUND BACKGROUND
The 3-minute chair rise test (3-minute CRT) and the Disability Related to COPD Tool (DIRECT) are two reproducible and valid short tests that can assess the benefit of pulmonary rehabilitation (PR) in terms of functional capacity and dyspnea in everyday activities.
METHODS METHODS
We determined the minimal clinically important difference (MCID) of the DIRECT questionnaire and 3-minute CRT using distribution methods and anchor encroaches with a panel of eight standard tests in a cohort of 116 COPD patients who completed a PR program in real-life settings.
RESULTS RESULTS
The estimated MCID for the 3-minute CRT and DIRECT scores was five repetitions and two units, respectively, using separate and combined independent anchors. The all-patient (body mass index-obstruction-dyspnea-exercise [BODE] scores 0-7), BODE 0-2 (n=42), and BODE 3-4 (n=50) groups showed improvements greater than the MCID in most tests and questionnaires used. In contrast, the BODE 5-7 group (n=24) showed improvements greater than MCID in only the 3-minute CRT, 6-minute walk test, endurance exercise test, and DIRECT questionnaire.
DISCUSSION AND CONCLUSION CONCLUSIONS
This study demonstrates that the short and simple DIRECT questionnaire and 3-minute CRT are responsive to capture the beneficial effects of a PR program in COPD patients, including those with severe disease.
TRIAL REGISTRATION NUMBER BACKGROUND
NCT03286660.

Identifiants

pubmed: 30774324
doi: 10.2147/COPD.S187567
pii: copd-14-261
pmc: PMC6349077
doi:

Banques de données

ClinicalTrials.gov
['NCT03286660']

Types de publication

Comparative Study Journal Article Multicenter Study Observational Study

Langues

eng

Pagination

261-269

Déclaration de conflit d'intérêts

Disclosure Financial support for this study was provided by an unrestricted grant from Boehringer Ingelheim, France. BA reports grants and other from Boehringer Ingelheim, France, during the conduct of the study. The authors report no other conflicts of interest in this work.

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Auteurs

Jonathan Lévesque (J)

Department of Medicine, Pneumology Service, Hôpital Maisonneuve-Rosemont, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada.

Anestis Antoniadis (A)

Laboratoire Jean Kuntzmann UMR5224, Statistics Department, Université Grenoble-Alpes, Grenoble, France.

Pei Zhi Li (PZ)

Montreal Chest Institute, McGill University Health Center Research Institute, McGill University, Montreal, Quebec, Canada.

Frédéric Herengt (F)

Centre de Réadaptation Cardio-Respiratoire-Dieulefit Santé, Dieulefit, France.

Christophe Brosson (C)

Private Physiotherapist, Cours Liberation, Grenoble, France.

Jean-Marie Grosbois (JM)

Pneumology Service, Centre Hospitalier de Béthune, Béthune, France.

Alain Bernady (A)

Toki-Eder Centre Médical Cardio-Respiratoire, Cambo-les-Bains, France.

Anthony Bender (A)

Private Physiotherapist, Boulevard de Metz Mont-Saint-Martin, France.
LUNEX International University of Health, Exercise and Sports, Differdange, Luxembourg.

Murielle Favre (M)

Centre de Pneumologie Henri Bazire, Saint-Julien-de-Ratz, France.

Antoine Guerder (A)

AP-HP, Groupe Hospitalier Pitié-Salpêtrière Charles Foix, Service de Pneumologie, Médecine Intensive et Réanimation, Département R3S, Paris, France.

Pascale Surpas (P)

Centre Médical de Bayère, Charnay, France.

Thomas Similowski (T)

AP-HP, Groupe Hospitalier Pitié-Salpêtrière Charles Foix, Service de Pneumologie, Médecine Intensive et Réanimation, Département R3S, Paris, France.
Sorbonne Université, INSERM, UMRS1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France.

Bernard Aguilaniu (B)

Faculty of Medicine, Université Grenoble-Alpes, Grenoble, France, b.aguilaniu@icloud.com.

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Classifications MeSH