Chemical and photochemical DNA "gears" reversibly control stiffness, shape-memory, self-healing and controlled release properties of polyacrylamide hydrogels.


Journal

Chemical science
ISSN: 2041-6520
Titre abrégé: Chem Sci
Pays: England
ID NLM: 101545951

Informations de publication

Date de publication:
28 Jan 2019
Historique:
received: 26 09 2018
accepted: 29 10 2018
entrez: 19 2 2019
pubmed: 19 2 2019
medline: 19 2 2019
Statut: epublish

Résumé

A new class of stimuli-responsive DNA-based polyacrylamide hydrogels is described. They consist of glucosamine-boronate ester-crosslinked polyacrylamide chains being cooperatively bridged by stimuli-responsive nucleic acids. The triggered closure and dissociation of the stimuli-responsive units lead to switchable stiffness properties of the hydrogel. One hydrogel includes glucosamine-boronate esters and K

Identifiants

pubmed: 30774895
doi: 10.1039/c8sc04292f
pii: c8sc04292f
pmc: PMC6346408
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1008-1016

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Auteurs

Xia Liu (X)

Institute of Chemistry , The Center for Nanoscience and Nanotechnology , The Hebrew University of Jerusalem , Jerusalem , 91904 , Israel . Email: willnea@vms.huji.ac.il ; ; Tel: +972-2-6585272.

Junji Zhang (J)

Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering , Feringa Nobel Prize Scientist Joint Research Center , School of Chemistry and Molecular Engineering , East China University of Science & Technology , 130 Meilong Road , Shanghai 200237 , China.

Michael Fadeev (M)

Institute of Chemistry , The Center for Nanoscience and Nanotechnology , The Hebrew University of Jerusalem , Jerusalem , 91904 , Israel . Email: willnea@vms.huji.ac.il ; ; Tel: +972-2-6585272.

Ziyuan Li (Z)

Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering , Feringa Nobel Prize Scientist Joint Research Center , School of Chemistry and Molecular Engineering , East China University of Science & Technology , 130 Meilong Road , Shanghai 200237 , China.

Verena Wulf (V)

Institute of Chemistry , The Center for Nanoscience and Nanotechnology , The Hebrew University of Jerusalem , Jerusalem , 91904 , Israel . Email: willnea@vms.huji.ac.il ; ; Tel: +972-2-6585272.

He Tian (H)

Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering , Feringa Nobel Prize Scientist Joint Research Center , School of Chemistry and Molecular Engineering , East China University of Science & Technology , 130 Meilong Road , Shanghai 200237 , China.

Itamar Willner (I)

Institute of Chemistry , The Center for Nanoscience and Nanotechnology , The Hebrew University of Jerusalem , Jerusalem , 91904 , Israel . Email: willnea@vms.huji.ac.il ; ; Tel: +972-2-6585272.

Classifications MeSH