Health-related quality of life worsens by school age amongst children with food allergy.

Children Food allergy Food hypersensitivity Health-related quality of life

Journal

Clinical and translational allergy
ISSN: 2045-7022
Titre abrégé: Clin Transl Allergy
Pays: England
ID NLM: 101576043

Informations de publication

Date de publication:
2019
Historique:
received: 27 11 2018
accepted: 04 01 2019
entrez: 19 2 2019
pubmed: 19 2 2019
medline: 19 2 2019
Statut: epublish

Résumé

Food allergy is negatively associated with health-related quality of life (HRQL). Although differences exist between parents and children, less is known about age-specific differences amongst children. As such, we aimed to identify if age, as well as other factors, are associated with food allergy-specific HRQL in an objectively defined population of children. Overall, 63 children (boys: n = 36; 57.1%) with specialist-diagnosed food allergy to 1 + foods were included. Parents/guardians completed the Swedish version of a disease-specific questionnaire designed to assess overall- and domain-specific HRQL. Descriptive statistics and linear regression were used. The most common food allergy was hen's egg (n = 40/63; 63.5%). Most children had more than one food allergy (n = 48; 76.2%). Nearly all had experienced mild symptoms (e.g. skin; n = 56/63; 94.9%), and more than half had severe symptoms (e.g. respiratory; 39/63; 66.1%). Compared to young children (0-5 years), older children (6-12 years) had worse HRQL (e.g. overall HRQL: B = 0.60; 95% CI 0.05-1.16; Older children and those with severe food allergy have worse HRQL.

Sections du résumé

BACKGROUND BACKGROUND
Food allergy is negatively associated with health-related quality of life (HRQL). Although differences exist between parents and children, less is known about age-specific differences amongst children. As such, we aimed to identify if age, as well as other factors, are associated with food allergy-specific HRQL in an objectively defined population of children.
METHODS METHODS
Overall, 63 children (boys: n = 36; 57.1%) with specialist-diagnosed food allergy to 1 + foods were included. Parents/guardians completed the Swedish version of a disease-specific questionnaire designed to assess overall- and domain-specific HRQL. Descriptive statistics and linear regression were used.
RESULTS RESULTS
The most common food allergy was hen's egg (n = 40/63; 63.5%). Most children had more than one food allergy (n = 48; 76.2%). Nearly all had experienced mild symptoms (e.g. skin; n = 56/63; 94.9%), and more than half had severe symptoms (e.g. respiratory; 39/63; 66.1%). Compared to young children (0-5 years), older children (6-12 years) had worse HRQL (e.g. overall HRQL: B = 0.60; 95% CI 0.05-1.16;
CONCLUSION CONCLUSIONS
Older children and those with severe food allergy have worse HRQL.

Identifiants

pubmed: 30774928
doi: 10.1186/s13601-019-0244-0
pii: 244
pmc: PMC6366088
doi:

Types de publication

Journal Article

Langues

eng

Pagination

10

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Auteurs

Victoria Thörnqvist (V)

1The Centre for Allergy Research, Karolinska Institutet, Box 210, 171 77 Stockholm, Sweden.
2The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

Roelinde Middelveld (R)

1The Centre for Allergy Research, Karolinska Institutet, Box 210, 171 77 Stockholm, Sweden.
2The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

Hay Mar Wai (HM)

1The Centre for Allergy Research, Karolinska Institutet, Box 210, 171 77 Stockholm, Sweden.
2The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

Natalia Ballardini (N)

2The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
3Sachs' Children and Youth Hospital, Sodersjukhuset, Stockholm, Sweden.

Evalill Nilsson (E)

5Department of Medical and Health Sciences, Linköping University, Linköping, Sweden.

Jennie Strömquist (J)

4Pediatric Allergy, Linköpings Universitetet, Linköping, Sweden.

Staffan Ahlstedt (S)

1The Centre for Allergy Research, Karolinska Institutet, Box 210, 171 77 Stockholm, Sweden.
2The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

Lennart Jan Nilsson (LJ)

4Pediatric Allergy, Linköpings Universitetet, Linköping, Sweden.

Jennifer L P Protudjer (JLP)

1The Centre for Allergy Research, Karolinska Institutet, Box 210, 171 77 Stockholm, Sweden.
2The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
6Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Canada.
George and Fay Yee Centre for Healthcare Innovation, Winnipeg, Canada.
The Children's Health Research Institute of Manitoba, Winnipeg, Canada.

Classifications MeSH