The role of progesterone elevation in IVF.
Embryo quality
Endometrial receptivity
Implantation
In vitro fertilization
Progesterone elevation
Journal
Reproductive biology
ISSN: 2300-732X
Titre abrégé: Reprod Biol
Pays: Poland
ID NLM: 101160559
Informations de publication
Date de publication:
Mar 2019
Mar 2019
Historique:
received:
31
12
2018
revised:
04
02
2019
accepted:
07
02
2019
pubmed:
20
2
2019
medline:
5
9
2019
entrez:
20
2
2019
Statut:
ppublish
Résumé
Elevation of progesterone during the late follicular phase of stimulated in-vitro fertilization cycles is a frequent event, which negatively impacts the outcome. Over the years evidence has demonstrated a direct relationship between late-follicular elevated progesterone and endometrial receptivity. In this regard, elective cryopreservation of all good quality embryos and transfer in a subsequent frozen/thawed cycle is the most common strategy adopted by clinicians in case of elevated progesterone. Nonetheless, recent evidence suggests that elective cryopreservation might not entirely resolve the reduced pregnancy outcomes associated with the elevation of progesterone, considering that the increase may affect not only implantation, but also embryo quality.
Identifiants
pubmed: 30777675
pii: S1642-431X(18)30435-2
doi: 10.1016/j.repbio.2019.02.003
pii:
doi:
Substances chimiques
Progesterone
4G7DS2Q64Y
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1-5Informations de copyright
Copyright © 2019 Society for Biology of Reproduction & the Institute of Animal Reproduction and Food Research of Polish Academy of Sciences in Olsztyn. Published by Elsevier B.V. All rights reserved.