Membrane assisted continuous production of solvents with integrated solvent removal using liquid-liquid extraction.
Butyl butyrate extraction
Continuous butanol fermentation
High cell density culture
Membrane recycle fermentor
Pine sugars
Journal
Bioresource technology
ISSN: 1873-2976
Titre abrégé: Bioresour Technol
Pays: England
ID NLM: 9889523
Informations de publication
Date de publication:
May 2019
May 2019
Historique:
pubmed:
20
2
2019
medline:
24
8
2019
entrez:
20
2
2019
Statut:
ppublish
Résumé
The aim of this work was to demonstrate an industrially relevant pilot scale integrated process to produce butanol and other solvents from lignocellulosic sugars produced with AVAP® biomass fractionation technology from southern pine wood. The concentrated sugars were concurrently fermented using genetically engineered Clostridium acetobutylicum to n-butanol, acetone, isopropanol and ethanol in continuous membrane assisted cell recycle fermentation with steady-state solvent productivity exceeding 10 g/L/h. The solvents from the cell free permeate were recovered with extractant of butyl butyrate in a continuous liquid-liquid extraction column and aqueous product (raffinate) along with unused sugars, nutrients, and metabolic intermediates were recycled back to the fermentors. The total solvent yield approached 0.30 g/g sugars.
Identifiants
pubmed: 30780098
pii: S0960-8524(19)30203-2
doi: 10.1016/j.biortech.2019.02.024
pii:
doi:
Substances chimiques
Solvents
0
Types de publication
Journal Article
Langues
eng
Pagination
378-386Informations de copyright
Copyright © 2019 Elsevier Ltd. All rights reserved.