Low Endotoxin Recovery-Masking of Naturally Occurring Endotoxin.

bacterial endotoxin testing endotoxin limulus amoebocyte lysate lipopolysaccharide low endotoxin recovery masking naturally occurring endotoxin

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
15 Feb 2019
Historique:
received: 10 12 2018
revised: 08 02 2019
accepted: 12 02 2019
entrez: 21 2 2019
pubmed: 20 2 2019
medline: 1 6 2019
Statut: epublish

Résumé

Endotoxins are cell wall components of Gram-negative bacteria. A release of endotoxins into the human blood stream results in an inflammation reaction that can lead to life-threatening conditions like sepsis. Therefore, control for endotoxin contamination of intravenously administered drugs is crucial. Drugs are usually tested for putative endotoxin contamination with

Identifiants

pubmed: 30781342
pii: ijms20040838
doi: 10.3390/ijms20040838
pmc: PMC6412962
pii:
doi:

Substances chimiques

Endotoxins 0
Lipopolysaccharides 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Références

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Auteurs

Johannes Reich (J)

Microcoat Biotechnologie GmbH, Am Neuland 3, 82347 Bernried am Stanberger See, Germany. j.reich@microcoat.de.

Felix Alexander Weyer (FA)

Microcoat Biotechnologie GmbH, Am Neuland 3, 82347 Bernried am Stanberger See, Germany. f.weyer@microcoat.de.

Hiroshi Tamura (H)

LPS (Laboratory Program Support) Consulting Office, Tokyo 160-0023, Japan. htamura@lpsct.com.
Department of Host Defense and Biochemical Research, Juntendo University Graduate School of Medicine, Tokyo 113-8431, Japan. htamura@lpsct.com.

Isao Nagaoka (I)

Department of Host Defense and Biochemical Research, Juntendo University Graduate School of Medicine, Tokyo 113-8431, Japan. nagaokai@juntendo.ac.jp.

Hubert Motschmann (H)

Institute of Physical and Theoretical Chemistry, University of Regensburg, 93040 Regensburg, Germany. Hubert.Motschmann@chemie.uni-regensburg.de.

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Classifications MeSH