Complexin cooperates with Bruchpilot to tether synaptic vesicles to the active zone cytomatrix.
Adaptor Proteins, Signal Transducing
/ genetics
Adaptor Proteins, Vesicular Transport
/ genetics
Animals
Drosophila Proteins
/ genetics
Drosophila melanogaster
Mice
Mice, Knockout
Nerve Tissue Proteins
/ genetics
Neuronal Plasticity
Protein Domains
SNARE Proteins
/ genetics
Synaptic Vesicles
/ genetics
Journal
The Journal of cell biology
ISSN: 1540-8140
Titre abrégé: J Cell Biol
Pays: United States
ID NLM: 0375356
Informations de publication
Date de publication:
04 03 2019
04 03 2019
Historique:
received:
25
06
2018
revised:
14
12
2018
accepted:
09
01
2019
pubmed:
21
2
2019
medline:
11
2
2020
entrez:
21
2
2019
Statut:
ppublish
Résumé
Information processing by the nervous system depends on neurotransmitter release from synaptic vesicles (SVs) at the presynaptic active zone. Molecular components of the cytomatrix at the active zone (CAZ) regulate the final stages of the SV cycle preceding exocytosis and thereby shape the efficacy and plasticity of synaptic transmission. Part of this regulation is reflected by a physical association of SVs with filamentous CAZ structures via largely unknown protein interactions. The very C-terminal region of Bruchpilot (Brp), a key component of the
Identifiants
pubmed: 30782781
pii: jcb.201806155
doi: 10.1083/jcb.201806155
pmc: PMC6400551
doi:
Substances chimiques
Adaptor Proteins, Signal Transducing
0
Adaptor Proteins, Vesicular Transport
0
BRP protein, Drosophila
0
Cplx3 protein, mouse
0
Drosophila Proteins
0
Nerve Tissue Proteins
0
SNARE Proteins
0
cpx protein, Drosophila
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1011-1026Informations de copyright
© 2019 Scholz et al.
Références
Curr Biol. 2011 Jan 25;21(2):97-105
pubmed: 21215634
Neuron. 2010 Dec 9;68(5):803-6
pubmed: 21144993
Neuron. 2009 Jul 30;63(2):216-29
pubmed: 19640480
Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12055-60
pubmed: 12215497
J Neurosci. 2010 Oct 27;30(43):14340-5
pubmed: 20980589
Angew Chem Int Ed Engl. 2008;47(33):6172-6
pubmed: 18646237
J Vis Exp. 2015 Jan 20;(95):52139
pubmed: 25650626
Annu Rev Biochem. 1996;65:241-69
pubmed: 8811180
Neuron. 2014 Oct 22;84(2):416-31
pubmed: 25374362
Nature. 2000 Aug 24;406(6798):849-54
pubmed: 10972279
J Comp Physiol A. 1994 Aug;175(2):179-91
pubmed: 8071894
Genetics. 2004 Apr;166(4):1775-82
pubmed: 15126397
Cell Rep. 2014 Jul 10;8(1):94-102
pubmed: 24981865
J Neurosci. 2013 Oct 30;33(44):17253-63
pubmed: 24174659
J Microsc. 2010 Jan;237(1):12-22
pubmed: 20055915
Physiology (Bethesda). 2004 Oct;19:262-70
pubmed: 15381754
Trends Neurosci. 2013 Mar;36(3):185-94
pubmed: 23164531
Nat Methods. 2008 Feb;5(2):159-61
pubmed: 18176568
Nat Methods. 2006 Dec;3(12):995-1000
pubmed: 17072308
Nature. 2007 Jul 12;448(7150):151-6
pubmed: 17625558
Neuron. 2014 May 7;82(3):618-34
pubmed: 24811381
Neuron. 2006 Mar 16;49(6):833-44
pubmed: 16543132
J Comp Neurol. 2008 May 1;508(1):131-52
pubmed: 18302156
Curr Biol. 2011 Jan 25;21(2):106-13
pubmed: 21215631
Mol Cell Neurosci. 2013 Jan;52:161-72
pubmed: 23159779
Science. 2014 May 30;344(6187):1023-8
pubmed: 24876496
J Neurosci. 2004 Nov 17;24(46):10466-74
pubmed: 15548661
Cell Rep. 2013 May 30;3(5):1407-13
pubmed: 23643532
Traffic. 2008 Sep;9(9):1403-13
pubmed: 18445121
Neuron. 2012 Jul 12;75(1):11-25
pubmed: 22794257
Nat Protoc. 2011 Jun 16;6(7):991-1009
pubmed: 21720313
Nat Methods. 2012 Nov;9(11):1040-1
pubmed: 23132113
Nat Neurosci. 2007 Oct;10(10):1235-7
pubmed: 17873870
J Neurosci. 2016 Jun 22;36(25):6651-67
pubmed: 27335398
Cell. 2007 Nov 16;131(4):796-808
pubmed: 18022372
J Neurosci. 2017 Jan 11;37(2):383-396
pubmed: 28077717
Biochemistry. 2007 Jul 10;46(27):7963-72
pubmed: 17567046
J Cell Biol. 2005 May 23;169(4):669-80
pubmed: 15911881
Biophys J. 1997 May;72(5):2160-9
pubmed: 9129818
Traffic. 2015 Apr;16(4):338-64
pubmed: 25620674
Nat Genet. 2008 Apr;40(4):476-83
pubmed: 18311141
Front Synaptic Neurosci. 2010 Sep 16;2:144
pubmed: 21423530
Mol Cell Neurosci. 2013 Sep;56:244-54
pubmed: 23769723
Development. 1997 Feb;124(4):761-71
pubmed: 9043058
Annu Rev Physiol. 2002;64:355-405
pubmed: 11826273
HFSP J. 2010 Apr;4(2):72-84
pubmed: 20811513
Neuron. 2013 Jan 23;77(2):323-34
pubmed: 23352168
Neuron. 2015 Sep 23;87(6):1131-1142
pubmed: 26402599
Neuron. 2009 Nov 12;64(3):367-80
pubmed: 19914185
Genetics. 2001 May;158(1):209-20
pubmed: 11333231
Science. 2006 May 19;312(5776):1051-4
pubmed: 16614170
Cell Rep. 2016 Jun 7;15(10):2239-2250
pubmed: 27239031
Science. 2004 Mar 26;303(5666):2037-9
pubmed: 15044806
Proc Natl Acad Sci U S A. 1998 Apr 28;95(9):5323-8
pubmed: 9560274
Neuron. 2010 Nov 18;68(4):724-38
pubmed: 21092861
Nat Commun. 2014 Aug 18;5:4650
pubmed: 25130366
Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):17183-8
pubmed: 21903923
J Neurosci. 2011 Apr 20;31(16):6041-52
pubmed: 21508229
J Neurosci. 1999 Apr 15;19(8):3023-32
pubmed: 10191319
Development. 1993 Jun;118(2):401-15
pubmed: 8223268
Nat Neurosci. 2008 Jun;11(6):659-66
pubmed: 18469810
J Neurosci. 2004 Jan 7;24(1):282-5
pubmed: 14715960
Nat Neurosci. 2000 Sep;3(9):859-60
pubmed: 10966613
Neuron. 2016 Aug 17;91(4):777-791
pubmed: 27537483
Biophys J. 2008 Jun;94(12):4957-70
pubmed: 18326650
Mol Cell Neurosci. 2010 Dec;45(4):389-97
pubmed: 20678575
Front Cell Neurosci. 2015 Feb 05;9:29
pubmed: 25698934
J Cell Biol. 2009 Jul 13;186(1):129-45
pubmed: 19596851
Neuron. 2015 Nov 4;88(3):492-8
pubmed: 26539890
Nat Neurosci. 2011 Jul 24;14(9):1135-41
pubmed: 21785435
Nat Rev Neurosci. 2016 Feb;17(2):118-25
pubmed: 26806630
PLoS Biol. 2018 Apr 9;16(4):e2003611
pubmed: 29630591
Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7590-E7599
pubmed: 27821736
J Cell Sci. 2009 May 1;122(Pt 9):1352-61
pubmed: 19386896
Neuron. 2010 Nov 18;68(4):710-23
pubmed: 21092860
J Cell Biol. 2013 May 27;201(5):725-40
pubmed: 23712261
Gene Expr Patterns. 2009 Jun;9(5):371-80
pubmed: 19602393
Annu Rev Physiol. 2014;76:333-63
pubmed: 24274737
Neuron. 1999 Jun;23(2):399-409
pubmed: 10399944
J Cell Biol. 1963 Apr;17:208-12
pubmed: 13986422
Anal Chem. 2013 Mar 19;85(6):3393-400
pubmed: 23410003