Graphene nano-ribbon based high potential and efficiency for DNA, cancer therapy and drug delivery applications.


Journal

Drug metabolism reviews
ISSN: 1097-9883
Titre abrégé: Drug Metab Rev
Pays: England
ID NLM: 0322067

Informations de publication

Date de publication:
02 2019
Historique:
pubmed: 21 2 2019
medline: 31 12 2019
entrez: 21 2 2019
Statut: ppublish

Résumé

In this article, graphene oxide Nano ribbons (GONRs) and its high potential for using in medical fields have been reviewed. Recently, Graphene Nano ribbons (GNRs) has been a field of interest in biological methods and disease treatment such as drug delivery, DNA applications, and photothermal cancer therapies. GNRs demonstrate more efficient properties rather than other graphene-based Nanomaterials due to their larger surface area. These novel properties made them into a remarkable substitute material for biological fields as they have different cytotoxic effects and almost nontoxic to human health and the environment. In this study, some of the significant effects of GNRs such as Geno toxicity effects in human mesenchymal stem cells, DNA assembly, drug delivery agents, and the use of PEGylated GNRs in photothermal cancer therapy has been investigated.

Identifiants

pubmed: 30784324
doi: 10.1080/03602532.2019.1582661
doi:

Substances chimiques

graphene oxide 0
Graphite 7782-42-5
DNA 9007-49-2

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

91-104

Auteurs

Seyyed Mojtaba Mousavi (SM)

a Department of Medical Nanotechnology School of Advanced Medical Sciences and Technologies , Shiraz University of Medical Sciences , Shiraz , Iran.
b Pharmaceutical Sciences Research Center , Shiraz University of Medical Sciences , Shiraz , Iran.

Sadaf Soroshnia (S)

c Department of Chemical Engineering, University of Mohaghegh Ardabili (UMA) , Ardabil , Iran.

Seyyed Alireza Hashemi (SA)

a Department of Medical Nanotechnology School of Advanced Medical Sciences and Technologies , Shiraz University of Medical Sciences , Shiraz , Iran.
b Pharmaceutical Sciences Research Center , Shiraz University of Medical Sciences , Shiraz , Iran.

Aziz Babapoor (A)

c Department of Chemical Engineering, University of Mohaghegh Ardabili (UMA) , Ardabil , Iran.

Younes Ghasemi (Y)

a Department of Medical Nanotechnology School of Advanced Medical Sciences and Technologies , Shiraz University of Medical Sciences , Shiraz , Iran.

Amir Savardashtaki (A)

d Department of Medical Biotechnology, Faculty of Advanced Medical Sciences and Technology , Shiraz , Iran.

Ali Mohammad Amani (AM)

a Department of Medical Nanotechnology School of Advanced Medical Sciences and Technologies , Shiraz University of Medical Sciences , Shiraz , Iran.

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Classifications MeSH