Hodgkin's lymphoma, nephrotic syndrome, and echinococcosis cysts: an unusual association and literature review.


Journal

Pediatric hematology and oncology
ISSN: 1521-0669
Titre abrégé: Pediatr Hematol Oncol
Pays: England
ID NLM: 8700164

Informations de publication

Date de publication:
Feb 2019
Historique:
pubmed: 21 2 2019
medline: 6 5 2019
entrez: 21 2 2019
Statut: ppublish

Résumé

We present a 5-year-old female with minimal change nephrotic syndrome (MCNS). Within several months, she became steroid-dependent with progression of edema and ascites. Imaging studies revealed abnormal solid mass and liver cysts and she was diagnosed with both abdominal Hodgkin's lymphoma (cHD) and large hepatic cystic echinococcosis (CE). Association between MCNS and cHL or with CE has been described in the literature in adults and rarely in the pediatric population. We report, for the first time, a simultaneous occurrence of all three: MCNS, cHL, and CE. Literature review and suggested pathophysiologic mechanisms underlying this phenomenon are presented.

Identifiants

pubmed: 30784346
doi: 10.1080/08880018.2019.1571541
doi:

Types de publication

Case Reports Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

40-45

Auteurs

Michael Geylis (M)

a Pediatrics Department A, Soroka University Medical Center, and Faculty of Health Sciences , Ben-Gurion University of the Negev , Beer Sheva , Israel.

Guy Beck Rosen (GB)

b Pediatric Hematology Unit, Soroka University Medical Center, and Faculty of Health Sciences , Ben-Gurion University of the Negev , Beer Sheva , Israel.

Dana Danino (D)

c Pediatric Infectious Diseases Unit, Saban Pediatric Medical Center, Soroka University Medical Center, and Faculty of Health Sciences , Ben-Gurion University of the Negev , Beer Sheva , Israel.

Ruth Schreiber (R)

a Pediatrics Department A, Soroka University Medical Center, and Faculty of Health Sciences , Ben-Gurion University of the Negev , Beer Sheva , Israel.

Dima Hassan (D)

a Pediatrics Department A, Soroka University Medical Center, and Faculty of Health Sciences , Ben-Gurion University of the Negev , Beer Sheva , Israel.

Karen Nalbandyan (K)

d Department of Pathology, Soroka University Medical Center, and Faculty of Health Sciences , Ben-Gurion University of the Negev , Beer Sheva , Israel.

Amit Nahum (A)

a Pediatrics Department A, Soroka University Medical Center, and Faculty of Health Sciences , Ben-Gurion University of the Negev , Beer Sheva , Israel.

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Classifications MeSH