Pulse Pressure Variations and Plethysmographic Variability Index Measured at Ear Are Able to Predict Fluid Responsiveness in the Sitting Position for Neurosurgery.


Journal

Journal of neurosurgical anesthesiology
ISSN: 1537-1921
Titre abrégé: J Neurosurg Anesthesiol
Pays: United States
ID NLM: 8910749

Informations de publication

Date de publication:
Jul 2020
Historique:
pubmed: 23 2 2019
medline: 21 7 2021
entrez: 22 2 2019
Statut: ppublish

Résumé

Pulse pressure variation (PPV) and plethysmographic variability index (PVI), dynamic indicators of preload dependence based on heart-lung interactions, are used to predict fluid responsiveness in mechanically ventilated patients in the supine position. The sitting position for neurosurgery, by changing intrathoracic blood volume, could affect the capacity of PPV and PVI to predict fluid responsiveness. The aim of the study was to assess the ability of PPV and PVI to predict fluid responsiveness during general anesthesia in the sitting position. In total, 31 patients were included after settling in the sitting position but before surgery began. PPV, PVI with a finger sensor (PVI finger), and PVI with an ear sensor (PVI ear) were recorded before and after a fluid challenge of hydroxylethylstarch 250 mL over 10 minute. Esophageal Doppler was used to record stroke volume. Patients were defined as fluid responders if stroke volume increased by more than 10% after the fluid challenge. In total, 13 (42%) patients were fluid responders. PPV and PVI ear were higher in responders than in nonresponders before the fluid challenge (12±5 vs. 7±3; P=0.0005 and 14±5 vs. 8±3; P=0.001, respectively). Areas under the receiver-operating curves to predict fluid responsiveness were 0.87 for PPV (P<0.0001), 0.87 for PVI ear (P<0.0001), and 0.64 for PVI finger (P=0.17). PPV ≥8% or PVI ear ≥11% predicted fluid responsiveness with sensitivities of 83% for both, and specificities of 83% and 91%, respectively. However PVI ear data were not available in 26% of patients. PPV can be used to predict fluid responsiveness in the sitting position for neurosurgery.

Sections du résumé

BACKGROUND BACKGROUND
Pulse pressure variation (PPV) and plethysmographic variability index (PVI), dynamic indicators of preload dependence based on heart-lung interactions, are used to predict fluid responsiveness in mechanically ventilated patients in the supine position. The sitting position for neurosurgery, by changing intrathoracic blood volume, could affect the capacity of PPV and PVI to predict fluid responsiveness. The aim of the study was to assess the ability of PPV and PVI to predict fluid responsiveness during general anesthesia in the sitting position.
METHODS METHODS
In total, 31 patients were included after settling in the sitting position but before surgery began. PPV, PVI with a finger sensor (PVI finger), and PVI with an ear sensor (PVI ear) were recorded before and after a fluid challenge of hydroxylethylstarch 250 mL over 10 minute. Esophageal Doppler was used to record stroke volume. Patients were defined as fluid responders if stroke volume increased by more than 10% after the fluid challenge.
RESULTS RESULTS
In total, 13 (42%) patients were fluid responders. PPV and PVI ear were higher in responders than in nonresponders before the fluid challenge (12±5 vs. 7±3; P=0.0005 and 14±5 vs. 8±3; P=0.001, respectively). Areas under the receiver-operating curves to predict fluid responsiveness were 0.87 for PPV (P<0.0001), 0.87 for PVI ear (P<0.0001), and 0.64 for PVI finger (P=0.17). PPV ≥8% or PVI ear ≥11% predicted fluid responsiveness with sensitivities of 83% for both, and specificities of 83% and 91%, respectively. However PVI ear data were not available in 26% of patients.
CONCLUSIONS CONCLUSIONS
PPV can be used to predict fluid responsiveness in the sitting position for neurosurgery.

Identifiants

pubmed: 30789383
doi: 10.1097/ANA.0000000000000587
pii: 00008506-202007000-00012
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

263-267

Références

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Auteurs

Lionel Bapteste (L)

Department of Anesthesiology, Groupement Hospitalier Est.

Romain Carrillon (R)

Department of Anesthesiology, Groupement Hospitalier Est.

Stéphanie Javelier (S)

Department of Anesthesiology, Centre Hospitalier de Chalon sur Sâone.

Jacques Guyotat (J)

Department of Neurosurgery, Hôpital Pierre Wertheimer, Hospices Civils de Lyon.

François-P Desgranges (FP)

Department of Anesthesiology, Groupement Hospitalier Est.

Jean-J Lehot (JJ)

Department of Anesthesiology, Groupement Hospitalier Est.
Claude Bernard Lyon 1 University, Villeurbanne.
Health Services and Performance Research, Lyon, France.

Anne-C Lukaszewicz (AC)

Department of Anesthesiology, Groupement Hospitalier Est.
Claude Bernard Lyon 1 University, Villeurbanne.

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