The OncoAge Consortium: Linking Aging and Oncology from Bench to Bedside and Back Again.
aging
cancer
education
elderly
optimization
research
well-being
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
21 02 2019
21 02 2019
Historique:
received:
28
01
2019
revised:
17
02
2019
accepted:
19
02
2019
entrez:
24
2
2019
pubmed:
24
2
2019
medline:
24
2
2019
Statut:
epublish
Résumé
It is generally accepted that carcinogenesis and aging are two biological processes, which are known to be associated. Notably, the frequency of certain cancers (including lung cancer), increases significantly with the age of patients and there is now a wealth of data showing that multiple mechanisms leading to malignant transformation and to aging are interconnected, defining the so-called common biology of aging and cancer. OncoAge, a consortium launched in 2015, brings together the multidisciplinary expertise of leading public hospital services and academic laboratories to foster the transfer of scientific knowledge rapidly acquired in the fields of cancer biology and aging into innovative medical practice and silver economy development. This is achieved through the development of shared technical platforms (for research on genome stability, (epi)genetics, biobanking, immunology, metabolism, and artificial intelligence), clinical research projects, clinical trials, and education. OncoAge focuses mainly on two pilot pathologies, which benefit from the expertise of several members, namely lung and head and neck cancers. This review outlines the broad strategic directions and key advances of OncoAge and summarizes some of the issues faced by this consortium, as well as the short- and long-term perspectives.
Identifiants
pubmed: 30795607
pii: cancers11020250
doi: 10.3390/cancers11020250
pmc: PMC6406685
pii:
doi:
Types de publication
Journal Article
Langues
eng
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