Feasibility and Potential Benefits of an Exercise Intervention in a Male With Down Syndrome Undergoing High-Dose Chemotherapy for Acute Lymphoblastic Leukemia: A Case Report.


Journal

Integrative cancer therapies
ISSN: 1552-695X
Titre abrégé: Integr Cancer Ther
Pays: United States
ID NLM: 101128834

Informations de publication

Date de publication:
Historique:
entrez: 24 2 2019
pubmed: 24 2 2019
medline: 18 12 2019
Statut: ppublish

Résumé

In patients with hematological malignancies, exercise is studied as a supportive measure with potential benefits on therapy and disease-related side effects. However, clinical trials have not yet integrated people with Down syndrome (DS), although this disability is associated with an increased risk for hematological malignancies. Therefore, we examined safety and feasibility of a mixed-modality exercise intervention in a male with DS undergoing high-dose chemotherapy for acute lymphoblastic leukemia. Furthermore, physical capacity and fatigue were assessed. Exercise sessions took place 3 times/wk over a 5-week period. Adherence to the exercise program was 100%, and no serious adverse events occurred. In contrast to the training sessions, applied endurance testing was not feasible. Furthermore, maintenance of fatigue level was observed. In conclusion, cancer patients with DS suffering from leukemia should not be excluded from physical activity or exercise programs.

Identifiants

pubmed: 30795696
doi: 10.1177/1534735419832358
pmc: PMC6432678
doi:

Types de publication

Case Reports Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1534735419832358

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Auteurs

Linda Bühl (L)

1 German Sport University Cologne, Germany.

Thomas Abel (T)

1 German Sport University Cologne, Germany.

Florian Wolf (F)

1 German Sport University Cologne, Germany.

Max Oberste (M)

1 German Sport University Cologne, Germany.

Wilhelm Bloch (W)

1 German Sport University Cologne, Germany.

Michael Hallek (M)

2 University of Cologne, Germany.

Thomas Elter (T)

2 University of Cologne, Germany.

Philipp Zimmer (P)

1 German Sport University Cologne, Germany.
3 German Cancer Research Center, Heidelberg, Germany.

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Classifications MeSH