Axin proteolysis by Iduna is required for the regulation of stem cell proliferation and intestinal homeostasis in
Animals
Axin Protein
/ metabolism
CRISPR-Cas Systems
Cell Proliferation
Crosses, Genetic
Drosophila Proteins
/ metabolism
Drosophila melanogaster
/ metabolism
Female
Gene Expression Regulation, Developmental
Green Fluorescent Proteins
/ metabolism
Homeostasis
Intestines
/ physiology
Male
Models, Genetic
Mutation
Poly-ADP-Ribose Binding Proteins
/ metabolism
RNA Interference
Recombinant Proteins
/ metabolism
Signal Transduction
Stem Cells
/ cytology
Tankyrases
/ metabolism
Ubiquitin-Protein Ligases
/ metabolism
Wnt1 Protein
/ metabolism
ADP-ribosylation
Axin
Protein degradation
Stem cells
Ubiquitin E3 ligase
Wingless
Journal
Development (Cambridge, England)
ISSN: 1477-9129
Titre abrégé: Development
Pays: England
ID NLM: 8701744
Informations de publication
Date de publication:
15 03 2019
15 03 2019
Historique:
received:
26
06
2018
accepted:
18
02
2019
pubmed:
24
2
2019
medline:
7
1
2020
entrez:
24
2
2019
Statut:
epublish
Résumé
Self-renewal of intestinal stem cells is controlled by Wingless/Wnt-β catenin signaling in both
Identifiants
pubmed: 30796047
pii: dev.169284
doi: 10.1242/dev.169284
pmc: PMC6451324
pii:
doi:
Substances chimiques
Axin Protein
0
Axn protein, Drosophila
0
Drosophila Proteins
0
Poly-ADP-Ribose Binding Proteins
0
Recombinant Proteins
0
Rnf146 protein, Drosophila
0
Wnt1 Protein
0
wg protein, Drosophila
0
Green Fluorescent Proteins
147336-22-9
Ubiquitin-Protein Ligases
EC 2.3.2.27
Tankyrases
EC 2.4.2.30
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NIGMS NIH HHS
ID : R01 GM060124
Pays : United States
Informations de copyright
© 2019. Published by The Company of Biologists Ltd.
Déclaration de conflit d'intérêts
Competing interestsThe authors declare no competing or financial interests.
Références
Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):E2967-76
pubmed: 25002478
PLoS One. 2008 Jul 09;3(7):e2639
pubmed: 18612384
Development. 2002 Dec;129(23):5437-47
pubmed: 12403714
Science. 1991 Aug 9;253(5020):665-9
pubmed: 1651563
Cell. 2002 Apr 5;109(1):47-60
pubmed: 11955446
Cell. 2012 Jun 8;149(6):1192-205
pubmed: 22682243
Nature. 2006 Jan 26;439(7075):475-9
pubmed: 16340959
Genetics. 2016 May;203(1):269-81
pubmed: 26975665
Trends Mol Med. 2012 Aug;18(8):483-93
pubmed: 22796206
Science. 1997 Mar 21;275(5307):1784-7
pubmed: 9065401
Gene Expr Patterns. 2007 Jan;7(3):323-31
pubmed: 17008134
Genes Dev. 2000 Dec 15;14(24):3140-52
pubmed: 11124806
Science. 1997 Mar 21;275(5307):1790-2
pubmed: 9065403
Nat Rev Mol Cell Biol. 2012 Jun 20;13(7):411-24
pubmed: 22713970
Mol Cell Biol. 2007 Nov;27(21):7551-9
pubmed: 17785439
Genetics. 2013 Aug;194(4):1029-35
pubmed: 23709638
Nat Cell Biol. 2011 May;13(5):623-9
pubmed: 21478859
JAKSTAT. 2013 Jul 1;2(3):e25408
pubmed: 24069565
J Clin Invest. 2017 Jun 30;127(7):2612-2625
pubmed: 28581440
Cell. 2012 Jun 8;149(6):1245-56
pubmed: 22682247
Nature. 2008 Oct 23;455(7216):1119-23
pubmed: 18806781
Cell. 2013 Apr 25;153(3):614-27
pubmed: 23622245
Nature. 2009 Oct 1;461(7264):614-20
pubmed: 19759537
Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4530-5
pubmed: 24616500
Science. 1997 Mar 21;275(5307):1787-90
pubmed: 9065402
Mol Cell. 2000 Mar;5(3):523-32
pubmed: 10882137
Cell. 2009 Jun 26;137(7):1343-55
pubmed: 19563763
Mol Cell. 2015 Jun 18;58(6):947-58
pubmed: 26091343
Dev Biol. 2011 Jun 1;354(1):31-43
pubmed: 21440535
PLoS One. 2011;6(7):e22595
pubmed: 21799911
J Clin Invest. 2017 Apr 3;127(4):1303-1315
pubmed: 28287403
Nature. 2015 Jan 8;517(7533):223-6
pubmed: 25327252
Nat Genet. 1998 Aug;19(4):379-83
pubmed: 9697701
Dev Biol. 2013 Jan 15;373(2):383-93
pubmed: 23110761
Cell Rep. 2013 May 30;3(5):1725-38
pubmed: 23643535
Methods. 1998 Apr;14(4):355-65
pubmed: 9608507
Development. 2016 May 15;143(10):1710-20
pubmed: 27190037
EMBO J. 2012 Oct 3;31(19):3901-17
pubmed: 22948071
Genetics. 2014 Apr;196(4):961-71
pubmed: 24478335
Dev Cell. 2018 Oct 8;47(1):112-121.e3
pubmed: 30220570
Biochem Biophys Res Commun. 2018 Sep 18;503(4):2234-2239
pubmed: 29953853
J Biol Chem. 2016 Jun 10;291(24):12747-60
pubmed: 27068743
Nature. 2006 Jan 26;439(7075):470-4
pubmed: 16340960
Development. 2005 Mar;132(6):1443-51
pubmed: 15716339
Nat Commun. 2016 May 03;7:11430
pubmed: 27138857
Mol Cell Biol. 2006 Mar;26(6):2044-54
pubmed: 16507985
Cell Signal. 2014 Aug;26(8):1717-24
pubmed: 24768997
PLoS Genet. 2016 Feb 04;12(2):e1005822
pubmed: 26845150
Science. 1999 Mar 12;283(5408):1739-42
pubmed: 10073940
Bioorg Med Chem Lett. 2009 Jul 15;19(14):3825-7
pubmed: 19410457
Oncogene. 2000 May 15;19(21):2598-606
pubmed: 10851058
PLoS Biol. 2003 Oct;1(1):E10
pubmed: 14551908
Science. 1991 Aug 9;253(5020):661-5
pubmed: 1651562
Nat Rev Drug Discov. 2012 Dec;11(12):923-36
pubmed: 23197039
Cell. 2017 Jun 1;169(6):985-999
pubmed: 28575679