Choroidal vasculature imaging with laser Doppler holography.


Journal

Biomedical optics express
ISSN: 2156-7085
Titre abrégé: Biomed Opt Express
Pays: United States
ID NLM: 101540630

Informations de publication

Date de publication:
01 Feb 2019
Historique:
received: 23 11 2018
revised: 09 01 2019
accepted: 10 01 2019
entrez: 26 2 2019
pubmed: 26 2 2019
medline: 26 2 2019
Statut: epublish

Résumé

The choroid is a highly vascularized tissue supplying the retinal pigment epithelium and photoreceptors. Its implication in retinal diseases is gaining increasing interest. However, investigating the anatomy and flow of the choroid remains challenging. Here we show that laser Doppler holography provides high-contrast imaging of choroidal vessels in humans, with a spatial resolution comparable to state-of-the-art indocyanine green angiography and optical coherence tomography. Additionally, laser Doppler holography contributes to sort out choroidal arteries and veins by using a power Doppler spectral analysis. We thus demonstrate the potential of laser Doppler holography to improve our understanding of the anatomy and flow of the choroidal vascular network.

Identifiants

pubmed: 30800528
doi: 10.1364/BOE.10.000995
pii: 349873
pmc: PMC6377881
doi:

Types de publication

Journal Article

Langues

eng

Pagination

995-1012

Déclaration de conflit d'intérêts

The authors declare that there are no conflicts of interest related to this article.

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Auteurs

Léo Puyo (L)

Institut Langevin, Centre National de la Recherche Scientifique (CNRS), Paris Sciences & Lettres (PSL University), École Supérieure de Physique et de Chimie Industrielles (ESPCI Paris), 1 rue Jussieu, 75005 Paris, France.
Paris Adaptive Optics, Retinal Imaging, and Surgery, (PARIS) Group, France.

Michel Paques (M)

Paris Adaptive Optics, Retinal Imaging, and Surgery, (PARIS) Group, France.
Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, INSERM-DHOS CIC 1423, 28 rue de Charenton, 75012 Paris, France.
Institut de la Vision-Sorbonne Universités, 17 rue Moreau, 75012 Paris, France.

Mathias Fink (M)

Institut Langevin, Centre National de la Recherche Scientifique (CNRS), Paris Sciences & Lettres (PSL University), École Supérieure de Physique et de Chimie Industrielles (ESPCI Paris), 1 rue Jussieu, 75005 Paris, France.
Paris Adaptive Optics, Retinal Imaging, and Surgery, (PARIS) Group, France.

José-Alain Sahel (JA)

Paris Adaptive Optics, Retinal Imaging, and Surgery, (PARIS) Group, France.
Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, INSERM-DHOS CIC 1423, 28 rue de Charenton, 75012 Paris, France.
Institut de la Vision-Sorbonne Universités, 17 rue Moreau, 75012 Paris, France.

Michael Atlan (M)

Institut Langevin, Centre National de la Recherche Scientifique (CNRS), Paris Sciences & Lettres (PSL University), École Supérieure de Physique et de Chimie Industrielles (ESPCI Paris), 1 rue Jussieu, 75005 Paris, France.
Paris Adaptive Optics, Retinal Imaging, and Surgery, (PARIS) Group, France.

Classifications MeSH