The Clinical Outcomes in Patients with Critical Limb Ischemia One Year after Spinal Cord Stimulation.
Aged
Biomarkers
/ blood
Blood Gas Monitoring, Transcutaneous
Critical Illness
Female
Humans
Ischemia
/ blood
Male
Microcirculation
Middle Aged
Oxygen
/ blood
Peripheral Arterial Disease
/ blood
Prospective Studies
Recovery of Function
Regional Blood Flow
Spinal Cord Stimulation
Time Factors
Treatment Outcome
Journal
Annals of vascular surgery
ISSN: 1615-5947
Titre abrégé: Ann Vasc Surg
Pays: Netherlands
ID NLM: 8703941
Informations de publication
Date de publication:
Jan 2020
Jan 2020
Historique:
received:
17
10
2018
revised:
19
12
2018
accepted:
20
12
2018
pubmed:
26
2
2019
medline:
14
4
2020
entrez:
26
2
2019
Statut:
ppublish
Résumé
The aim of this study was to evaluate the long-term outcomes of spinal cord stimulation in patients with critical limb ischemia and to test the hypothesis that the dynamics of clinical changes one year after therapy depend both on the clinical determinants associated with the underlying disease and on factors related to systemic atherosclerosis. This prospective cohort study included 56 patients with critical limb ischemia. All patients before and after spinal cord stimulation were examined in terms of the dynamics of their clinical changes using the Rutherford scale and transcutaneous oxygen tension (TcPO One year after spinal cord stimulation, 74% of patients showed positive clinical outcomes. No changes were observed in 9.3% of patients, whereas adverse clinical outcomes were revealed in 16.7% of cases. The TcPO The positive clinical outcomes were revealed in most patients with critical limb ischemia one year after spinal cord stimulation. The low values of peripheral tissue metabolism with the disturbed functional status of the microvasculature are associated with the negative clinical outcome. The patients with baseline TcPO
Sections du résumé
BACKGROUND
BACKGROUND
The aim of this study was to evaluate the long-term outcomes of spinal cord stimulation in patients with critical limb ischemia and to test the hypothesis that the dynamics of clinical changes one year after therapy depend both on the clinical determinants associated with the underlying disease and on factors related to systemic atherosclerosis.
METHODS
METHODS
This prospective cohort study included 56 patients with critical limb ischemia. All patients before and after spinal cord stimulation were examined in terms of the dynamics of their clinical changes using the Rutherford scale and transcutaneous oxygen tension (TcPO
RESULTS
RESULTS
One year after spinal cord stimulation, 74% of patients showed positive clinical outcomes. No changes were observed in 9.3% of patients, whereas adverse clinical outcomes were revealed in 16.7% of cases. The TcPO
CONCLUSIONS
CONCLUSIONS
The positive clinical outcomes were revealed in most patients with critical limb ischemia one year after spinal cord stimulation. The low values of peripheral tissue metabolism with the disturbed functional status of the microvasculature are associated with the negative clinical outcome. The patients with baseline TcPO
Identifiants
pubmed: 30802587
pii: S0890-5096(19)30171-2
doi: 10.1016/j.avsg.2018.12.093
pii:
doi:
Substances chimiques
Biomarkers
0
Oxygen
S88TT14065
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
356-364Informations de copyright
Copyright © 2019 Elsevier Inc. All rights reserved.