The impact of catheter ablation for atrial fibrillation in heart failure.
atrial fibrillation
catheter ablation
heart failure
meta‐analysis
pulmonary vein isolation
Journal
Journal of arrhythmia
ISSN: 1880-4276
Titre abrégé: J Arrhythm
Pays: Japan
ID NLM: 101263026
Informations de publication
Date de publication:
Feb 2019
Feb 2019
Historique:
received:
07
07
2018
revised:
30
07
2018
accepted:
01
08
2018
entrez:
27
2
2019
pubmed:
26
2
2019
medline:
26
2
2019
Statut:
epublish
Résumé
Atrial fibrillation (AF) commonly co-exists with systolic heart failure (SHF) and its presence is associated with a worse prognosis. Despite this, a rhythm control approach using antiarrhythmic drugs (AADs) to reduce AF burden has demonstrated no prognostic benefit. Catheter ablation (AFA) is more effective than AADs at reducing AF burden. We performed a meta-analysis to evaluate the impact of AFA on outcomes in SHF. Electronic databases were systematically searched. We included only randomized controlled trials that examined the impact of AFA on clinical outcomes in patients with SHF (LVEF <50%). We included studies with any ablation strategy that incorporated pulmonary vein isolation and any control group. Seven studies (n = 858) were included with a mean follow-up of 6-38 months. In comparison to controls, AFA was associated with significant reductions in all-cause mortality (relative risk [RR] 0.52,
Identifiants
pubmed: 30805042
doi: 10.1002/joa3.12115
pii: JOA312115
pmc: PMC6373662
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
33-42Subventions
Organisme : British Heart Foundation
ID : FS/14/77/30913
Pays : United Kingdom
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