Obstructive sleep apnea and comorbidities: a dangerous liaison.
COPD
Mortality
asthma
cancer
cardiovascular disease
diabetes
prognosis
Journal
Multidisciplinary respiratory medicine
ISSN: 1828-695X
Titre abrégé: Multidiscip Respir Med
Pays: Italy
ID NLM: 101477642
Informations de publication
Date de publication:
2019
2019
Historique:
received:
21
11
2018
accepted:
20
01
2019
entrez:
28
2
2019
pubmed:
28
2
2019
medline:
28
2
2019
Statut:
epublish
Résumé
Obstructive sleep apnea (OSA) is a highly prevalent disease, and is traditionally associated with increased cardiovascular risk. The role of comorbidities in OSA patients has emerged recently, and new conditions significantly associated with OSA are increasingly reported. A high comorbidity burden worsens prognosis, but some data suggest that CPAP might be protective especially in patients with comorbidities. Aim of this narrative review is to provide an update on recent studies, with special attention to cardiovascular and cerebrovascular comorbidities, the metabolic syndrome and type 2 diabetes, asthma, COPD and cancer. Better phenotypic characterization of OSA patients, including comorbidities, will help to provide better individualized care. The unsatisfactory adherence to CPAP in patients without daytime sleepiness should prompt clinicians to examine the overall risk profile of each patient in order to identify subjects at high risk for worse prognosis and provide the optimal treatment not only for OSA, but also for comorbidities.
Identifiants
pubmed: 30809382
doi: 10.1186/s40248-019-0172-9
pii: 172
pmc: PMC6374907
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
8Déclaration de conflit d'intérêts
Not applicable.Not applicable.The authors declare they have no competing interests.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
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