Economics of gastroenteropancreatic neuroendocrine tumors: a systematic review.

budget impact cost-of-illness costs economic burden economic evaluation gastroenteropancreatic neuroendocrine tumors resource utilization systematic review

Journal

Therapeutic advances in endocrinology and metabolism
ISSN: 2042-0188
Titre abrégé: Ther Adv Endocrinol Metab
Pays: United States
ID NLM: 101532143

Informations de publication

Date de publication:
2019
Historique:
received: 19 10 2018
accepted: 13 01 2019
entrez: 1 3 2019
pubmed: 1 3 2019
medline: 1 3 2019
Statut: epublish

Résumé

Despite current interest, enthusiasm and progress in the development of therapies for gastroenteropancreatic (GEP) neuroendocrine tumors (NETs), there are substantial gaps in the published literature regarding cost-of-illness analyses, economic evaluation and budget impact analyses. Compounding the issue is that data on resource utilization and cost-effectiveness of different diagnostic and therapeutic modalities for GEP-NETs are scarce. A systematic review on the economic impact of GEP-NETs was carried out using four databases: The 14 studies selected included cost-of-illness analyses ( There is a lack of data related to resource utilization in the field of GEP-NETs. Therefore, cost-effectiveness and budget impact studies of existing and emerging treatments are urgently needed to help the decision-making process for patients with NETs.

Sections du résumé

BACKGROUND BACKGROUND
Despite current interest, enthusiasm and progress in the development of therapies for gastroenteropancreatic (GEP) neuroendocrine tumors (NETs), there are substantial gaps in the published literature regarding cost-of-illness analyses, economic evaluation and budget impact analyses. Compounding the issue is that data on resource utilization and cost-effectiveness of different diagnostic and therapeutic modalities for GEP-NETs are scarce.
METHODS METHODS
A systematic review on the economic impact of GEP-NETs was carried out using four databases:
RESULTS RESULTS
The 14 studies selected included cost-of-illness analyses (
CONCLUSION CONCLUSIONS
There is a lack of data related to resource utilization in the field of GEP-NETs. Therefore, cost-effectiveness and budget impact studies of existing and emerging treatments are urgently needed to help the decision-making process for patients with NETs.

Identifiants

pubmed: 30815246
doi: 10.1177/2042018819828217
pii: 10.1177_2042018819828217
pmc: PMC6381439
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

2042018819828217

Déclaration de conflit d'intérêts

Conflict of interest statement: E.G. received honoraria as a speaker, and participated in advisory boards at Novartis, Pfizer, IPSE, Adacap and Lexicon. All other authors have no conflicts of interest to declare.

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Auteurs

Enrique Grande (E)

Department of Medical Oncology, Hospital Universitario Ramón y Cajal, Madrid, Spain.

Ángel Díaz (Á)

Department of Medical Oncology, Hospital Universitario Clínico San Carlos, Madrid, Spain.

Carlos López (C)

Department of Medical Oncology, Hospital Universitario Marqués de Valdecilla, Santander, Spain.

Javier Munarriz (J)

Department of Medical Oncology, Hospital Provincial de Castellón, Castellón, Spain.

Juan-José Reina (JJ)

Department of Medical Oncology, Hospital Virgen Macarena, Sevilla, Spain.

Ruth Vera (R)

Department of Medical Oncology, Complejo Hospitalario de Navarra, Pamplona, Spain.

Beatriz Bernárdez (B)

Department of Pharmacy, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain.

Javier Aller (J)

Department of Endocrinology, Hospital Universitario Puerta de Hierro, Madrid, Spain.

Jaume Capdevila (J)

Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, Barcelona, Spain.

Rocio Garcia-Carbonero (R)

Oncology Department, Hospital Universitario 12 de Octubre, IIS imas12, UCM, CNIO, CIBERONC, Madrid, Spain.

Paula Jimenez Fonseca (P)

Department of Medical Oncology, Hospital Central de Asturias, Oviedo, Spain.

Marta Trapero-Bertran (M)

Research Institute for Evaluation and Public Policies (IRAPP), Universitat Internacional de Catalunya (UIC), Carrer de la Immaculada, 22, Barcelona, 08017, Spain.

Classifications MeSH