Breakthrough invasive fungal diseases in acute myeloid leukemia patients receiving mould active triazole primary prophylaxis after intensive chemotherapy: An Italian consensus agreement on definitions and management.


Journal

Medical mycology
ISSN: 1460-2709
Titre abrégé: Med Mycol
Pays: England
ID NLM: 9815835

Informations de publication

Date de publication:
01 Apr 2019
Historique:
received: 05 07 2018
accepted: 27 09 2018
revised: 03 09 2018
entrez: 1 3 2019
pubmed: 1 3 2019
medline: 26 3 2019
Statut: ppublish

Résumé

In the attempt to establish definitions and provide shared approaches to breakthrough invasive fungal diseases (br-IFD) in acute myeloid leukemia (AML) patients submitted to intensive chemotherapy and receiving triazoles as mould active primary antifungal prophylaxis (MA-PAP), literature on br-IFD in AML patients receiving triazoles MA-PAP was reviewed and a Consensus Development Conference Project was convened. The following four candidate key-questions were generated and formed the set of questions of the present document: "definition of br-IFD," "diagnostic strategy during MA-PAP to detect br-IFD," "possible causes of MA-PAP failure," "management of br-IFD."

Identifiants

pubmed: 30816979
pii: 5366909
doi: 10.1093/mmy/myy091
doi:

Substances chimiques

Antifungal Agents 0
Triazoles 0

Types de publication

Consensus Development Conference Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

S127-S137

Informations de copyright

© The Author(s) 2019. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology.

Auteurs

Corrado Girmenia (C)

Dipartimento di Ematologia, Oncologia, e Dermatologia, Azienda Policlinico Umberto I, Rome.

Alessandro Busca (A)

A.O.U. Città della Salute e della Scienza, Dipartimento di Oncologia, SSD Trapianto allogenico di cellule staminali, Turin, Italy.

Anna Candoni (A)

Clinica Ematologica-Centro trapianti e Terapie Cellulari, Azienda Ospedaliero-Universitaria di Udine.

Simone Cesaro (S)

Oncoematologia Pediatrica, Azienda Ospedaliera Universitaria Integrata, Verona.

Mario Luppi (M)

Cattedra ed UO Ematologia. Dipartimento di Scienze Mediche e Chirurgiche Materno Infantile e dell' Adulto. AOU Modena. UNIMORE. Modena.

Anna Maria Nosari (AM)

Divisione di Ematologia e Centro Trapianti Midollo ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy.

Livio Pagano (L)

Istituto di Ematologia, Fondazione Policlinico A. Gemelli- IRCCS - Università Cattolica del Sacro Cuore, Rome.

Giuseppe Rossi (G)

S.C. Ematologia e Dipartimento Oncologia Medica Spedali Civili, Brescia.

Adriano Venditti (A)

Ematologia, Fondazione Policlinico Tor Vergata, Rome.

Franco Aversa (F)

Haematology and BMT Unit, University of Parma, Parma, Italy.

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Classifications MeSH