Assessment of maternal GBS colonization and early-onset neonatal disease rate for term deliveries: a decade perspective.
GBS colonization
Streptococcus agalactiae
early-onset disease
group B streptococcus (GBS)
pregnancy
universal screening
Journal
Journal of perinatal medicine
ISSN: 1619-3997
Titre abrégé: J Perinat Med
Pays: Germany
ID NLM: 0361031
Informations de publication
Date de publication:
26 Jul 2019
26 Jul 2019
Historique:
received:
07
09
2018
accepted:
24
01
2019
pubmed:
1
3
2019
medline:
17
1
2020
entrez:
1
3
2019
Statut:
ppublish
Résumé
Objective To assess the maternal group B streptococcal (GBS) colonization rate and neonatal early-onset GBS (EOGBS) disease in term deliveries, a decade apart. Methods This was a retrospective computerized study between 2005 and 2016. A universal GBS culture-based approach gradually replaced the GBS risk-oriented screening. A vaginal-rectal culture taken at 35-37 weeks was recorded at admission for delivery. Results We identified 149,910 term deliveries during the study period. GBS status was recorded in 53,879 (35.9%) cases. The GBS screening rate constantly increased from 20% in 2005 to 47.5% in 2016. GBS colonization rates significantly decreased, from 50.3% in 2005 to 31.7% in 2016, P<0.001. Overall, EOGBS disease was diagnosed in 37 term neonates (0.25 per 1000 live births.). The rate of EOGBS in neonates decreased dramatically from 0.361 per 1000 deliveries between 2005 and 2009 to 0.19 per 1000 deliveries between 2010 and 2016 (P<0.05). During the latter period, over 35% of the deliveries were screened for GBS. Remarkably, 64.9% of the EOGBS originated in the non-screened population. Conclusion The universal screening policy was associated with a significant decrease in neonatal EOGBS and therefore should be adopted. Further national surveillance studies should be performed in order to validate this approach.
Identifiants
pubmed: 30817304
doi: 10.1515/jpm-2018-0293
pii: jpm-2018-0293
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
528-533Références
Verani JR, McGee L, Schrag SJ. Prevention of perinatal Group B Streptococcal disease – revised guidelines from CDC, 2010. MMWR Recomm Rep 2010;59:1–36.
ACOG Committee Opinion: number 279, December 2002. Prevention of early-onset Group B Streptococcal disease in newborns. Obstet Gynecol 2002;100:1405–12.
Jordan HT, Farley MM, Craig A, Mohle-Boetani J, Harrison LH, Petit S, et al. Revisiting the need for vaccine prevention of late-onset neonatal Group B Streptococcal disease: a multistate, population-based analysis. Pediatr Infect Dis J 2008;27: 1057–64.
Weintraub Z, Regev R, Iancu TC, Ferne M, Rabinowitz BS. Perinatal group B streptococcal infections in Israel. Isr J Med Sci 1983;19:900–2.
Eidelman AI, Rudensky B, Ferne M, Weintraub G, Isacshon M. Epidemiology of group B streptococci in an Israeli hospital. Isr J Med Sci 1983;19:903–5.
Eidelman AI, Rudensky B, Turgeman D, Nubani N, Schimmel MS, Isacsohn M. Epidemiology of group B streptococci colonization and disease in mothers and infants: update of ongoing 10-year Jerusalem study. Isr J Med Sci 1990;26:71–3.
Schimmel MS, Eidelman AI, Rudensky B, Tadmor OP, Isacsohn M, Aboulafia Y, et al. Epidemiology of group B streptococcal colonization and infection in Jerusalem, 1989–1991. Isr J Med Sci 1994;30:349–51.
Marchaim D, Hallak M, Gortzak-Uzan L. Risk factors for carriage of group B streptococcus in southern Israel. Isr Med Assoc J 2003;5:646–8.
Eisenberg VH, Raveh D, Meislish Y, Rudensky B, Ezra Y, Samueloff A, et al. Prevention of early-onset neonatal group B streptococcal infection: is universal screening by culture universally applicable? Isr Med Assoc J 2006;8:698–702.
German L, Solt I, Bornstein J, Ben-Harush S, Ben-Elishai M, Weintraub Z. Is there an increase in the incidence of GBS carrier rates among pregnant women in northern Israel? Harefuah 2006;145:866–9, 944.
Dsc MH, Jabour A, Anton M, Hakim M, Kheirallah S. Screening Arab Israeli pregnant women for group B streptococcus by the AmpliVue GBS assay: are the rates higher than the national average? Isr Med Assoc J 2018;5:291–4.
Ginsberg GM, Eidelman AI, Shinwell E, Anis E, Peyser R, Lotan Y. Should Israel screen all mothers-to-be to prevent early-onset of neonatal group B streptococcal disease? A cost-utility analysis. Isr J Health Policy Res 2013;2:1.
Sefty H, Klivitsky A, Bromberg M, Dichtiar R, Ben Ami M, ShohatT, et al. Factors associated with choice of approach for Group B streptococcus screening. Isr J Health Policy Res 2016;5:42.
Cheng P-J, Chueh H-Y, Liu C-M, Hsu J-J, Hsieh T-T, Soong Y-K. Risk factors for recurrence of group B streptococcus colonization in a subsequent pregnancy. Obstet Gynecol 2008;111:704–9.
Money DM, Dobson S. The prevention of early-onset neonatal group B streptococcal disease. J Obstet Gynaecol Can 2004;26:826–40.
Hughes RG, Brocklehurst P, Steer PJ, Heath P, Stenson BM, on behalf of the Royal College of Obstetricians and Gynaecologists. Prevention of early-onset neonatal group B streptococcal disease: green-top guideline no 36. Br J Obstet Gynaecol 2017;124:e280–305.
Committee UKNS. UK NSC group B streptococcus (GBS) recommendation. London, UK: NSC; 2017.
Rodriguez-Granger J, Alvargonzalez JC, Berardi A, Berner R, Kunze M, Hufnagel M, et al. Prevention of group B streptococcal neonatal disease revisited. The DEVANI European project. Eur J Clin Microbiol Infect Dis 2012;31:2097–104.
Melin P, Efstratiou A. Group B streptococcal epidemiology and vaccine needs in developed countries. Vaccine 2013;31(Suppl 4):D31–42.
Tzialla C, Berardi A, Farina C, Clerici P, Borghesi A, Viora E, et al. Strategies for preventing group B streptococcal infections in newborns: a nation-wide survey of Italian policies. Ital J Pediatr 2017;43:1–7.
Sefty H, Friedman A, Shohat T. Incidence of early onset GBS sepsis final report 2010–2016; 2017. Available at: https://www.health.gov.il/PublicationsFiles/GBS.pdf. Accessed 1 Sep 2018.
Hakansson S, Axemo P, Bremme K, Bryngelsson AL, Wallin MC, Ekström CM, et al. Group B streptococcal carriage in Sweden: a national study on risk factors for mother and infant colonisation. Acta Obstet Gynecol Scand 2008;87:50–8.
Ma TWL, Chan V, So CH, Hui ASY, Lee CN, Hui APW, et al. Prevention of early onset group B streptococcal disease by universal antenatal culture-based screening in all public hospitals in Hong Kong. J Matern Fetal Neonatal Med 2018;31:881–7.
Cho CY, Tang YH, Chen YH, Wang SY, Yang YH, Wang TH, et al. Group B streptococcal infection in neonates and colonization in pregnant women: an epidemiological retrospective analysis. J Microbiol Immunol Infect 2017;pii: S1684-1182(17)30185-8. doi:10.1016/j.jmii.2017.08.004.
Phares CR, Lynfield R, Farley MM, Mohle-Boetani J, Harrison LH, Petit S, et al. Epidemiology of invasive group B streptococcal disease in the United States, 1999–2005. J Am Med Assoc 2008;299:2056–65.
Van Dyke MK, Phares CR, Lynfield R, Thomas AR, Arnold KE, Craig AS, et al. Evaluation of universal antenatal screening for group B streptococcus. N Engl J Med 2009;360:2626–36.