Current Risk Estimate of Breast Implant-Associated Anaplastic Large Cell Lymphoma in Textured Breast Implants.
Journal
Plastic and reconstructive surgery
ISSN: 1529-4242
Titre abrégé: Plast Reconstr Surg
Pays: United States
ID NLM: 1306050
Informations de publication
Date de publication:
03 2019
03 2019
Historique:
entrez:
1
3
2019
pubmed:
1
3
2019
medline:
4
4
2019
Statut:
ppublish
Résumé
With breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) now accepted as a unique (iatrogenic) subtype of ALCL directly associated with textured breast implants, we are now at a point where a sound epidemiologic profile and risk estimate are required. The aim of this article is to provide a comprehensive and up-to-date global review of the available epidemiologic data and literature relating to the incidence, risk, and prevalence of BIA-ALCL. All current literature relating to the epidemiology of BIA-ALCL was reviewed. Barriers relating to sound epidemiologic study were identified, and trends relating to geographical distribution, prevalence of breast implants, and implant characteristics were analyzed. Significant barriers exist to the accurate estimate of both the number of women with implants (denominator) and the number of cases of BIA-ALCL (numerator), including poor registries, underreporting, lack of awareness, cosmetic tourism, and fear of litigation. The incidence and risk of BIA-ALCL have increased dramatically from initial reports of 1 per million to current estimates of 1/2,832, and is largely dependant on the "population" (implant type and characteristics) examined and increased awareness of the disease. Although many barriers stand in the way of calculating accurate estimates of the incidence and risk of developing BIA-ALCL, steady progress, international registries, and collegiality between research teams are for the first time allowing early estimates. Most striking is the exponential rise in incidence over the last decade, which can largely be explained by the increasingly specific implant subtypes examined-driven by our understanding of the pathologic mechanism of the disease. High-textured high-surface area implants (grade 4 surface) carry the highest risk of BIA-ALCL (1/2,832).
Sections du résumé
BACKGROUND
With breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) now accepted as a unique (iatrogenic) subtype of ALCL directly associated with textured breast implants, we are now at a point where a sound epidemiologic profile and risk estimate are required. The aim of this article is to provide a comprehensive and up-to-date global review of the available epidemiologic data and literature relating to the incidence, risk, and prevalence of BIA-ALCL.
METHODS
All current literature relating to the epidemiology of BIA-ALCL was reviewed. Barriers relating to sound epidemiologic study were identified, and trends relating to geographical distribution, prevalence of breast implants, and implant characteristics were analyzed.
RESULTS
Significant barriers exist to the accurate estimate of both the number of women with implants (denominator) and the number of cases of BIA-ALCL (numerator), including poor registries, underreporting, lack of awareness, cosmetic tourism, and fear of litigation. The incidence and risk of BIA-ALCL have increased dramatically from initial reports of 1 per million to current estimates of 1/2,832, and is largely dependant on the "population" (implant type and characteristics) examined and increased awareness of the disease.
CONCLUSIONS
Although many barriers stand in the way of calculating accurate estimates of the incidence and risk of developing BIA-ALCL, steady progress, international registries, and collegiality between research teams are for the first time allowing early estimates. Most striking is the exponential rise in incidence over the last decade, which can largely be explained by the increasingly specific implant subtypes examined-driven by our understanding of the pathologic mechanism of the disease. High-textured high-surface area implants (grade 4 surface) carry the highest risk of BIA-ALCL (1/2,832).
Identifiants
pubmed: 30817554
doi: 10.1097/PRS.0000000000005567
pii: 00006534-201903001-00007
doi:
Types de publication
Comparative Study
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
30S-40SCommentaires et corrections
Type : CommentIn
Références
Brody GS, Deapen D, Taylor CR, et al.Anaplastic large cell lymphoma occurring in women with breast implants: analysis of 173 cases. Plast Reconstr Surg. 2015;135:695–705.
Keech JA, Creech BAnaplastic T-cell lymphoma in proximity to a saline-filled breast implant. Plast Reconstr Surg. 1997;100:554–555.
Clemens MW, Miranda RNComing of age: breast implant-associated anaplastic large cell lymphoma after 18 years of investigation. Clin Plast Surg. 2015;42:605–613.
Swerdlow SH, Campo E, Pileri SA, et al.The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood. 2016;127:2375–2390.
Jacobsen EAnaplastic large-cell lymphoma, T-/null-cell type. Oncologist. 2006;11:831–840.
Clemens MW, Medeiros LJ, Butler CE, et al.Complete surgical excision is essential for the management of patients with breast implant-associated anaplastic large-cell lymphoma. J Clin Oncol. 2016;34:160–168.
Cao YB, Wang SS, Huang HQ, et al.Primary breast lymphoma–a report of 27 cases with literature review. Ai Zheng. 2007;26:84–89.
Gholam D, Bibeau F, El Weshi A, et al.Primary breast lymphoma. Leuk Lymphoma. 2003;44:1173–1178.
Kim B, Roth C, Chung KC, et al.Anaplastic large cell lymphoma and breast implants: a systematic review. Plast Reconstr Surg. 2011;127:2141–2150.
Prince HM, Johnstone RCommentary on: biomarkers provide clues to early events in the pathogenesis of breast implant-associated anaplastic large cell lymphoma. Aesthet Surg J. 2016;36:782–783.
Loch-Wilkinson A, Beath KJ, Knight RJW, et al.Breast implant-associated anaplastic large cell lymphoma in Australia and New Zealand: high-surface-area textured implants are associated with increased risk. Plast Reconstr Surg. 2017;140:645–654.
Miranda RN, Aladily TN, Prince HM, et al.Breast implant-associated anaplastic large-cell lymphoma: long-term follow-up of 60 patients. J Clin Oncol. 2014;32:114–120.
Doren EL, Miranda RN, Selber JC, et al.U.S. epidemiology of breast implant-associated anaplastic large cell lymphoma. Plast Reconstr Surg. 2017;139:1042–1050.
Adrada BE, Miranda RN, Rauch GM, et al.Breast implant-associated anaplastic large cell lymphoma: sensitivity, specificity, and findings of imaging studies in 44 patients. Breast Cancer Res Treat. 2014;147:1–14.
Ashley FLFurther studies on the natural-Y breast prosthesis. Plast Reconstr Surg. 1972;49:414–419.
Henderson PW, Nash D, Laskowski M, et al.Objective comparison of commercially available breast implant devices. Aesthetic Plast Surg. 2015;39:724–732.
Sforza M, Zaccheddu R, Alleruzzo A, et al.Preliminary 3-year evaluation of experience with SilkSurface and VelvetSurface Motiva silicone breast implants: a single-center experience with 5813 consecutive breast augmentation cases. Aesthet Surg J. 2018;38(suppl_2):S62–S73.
Wong CH, Samuel M, Tan BK, et al.Capsular contracture in subglandular breast augmentation with textured versus smooth breast implants: a systematic review. Plast Reconstr Surg. 2006;118:1224–1236.
Barnsley GP, Sigurdson LJ, Barnsley SETextured surface breast implants in the prevention of capsular contracture among breast augmentation patients: a meta-analysis of randomized controlled trials. Plast Reconstr Surg. 2006;117:2182–2190.
Fagrell D, Berggren A, Tarpila ECapsular contracture around saline-filled fine textured and smooth mammary implants: a prospective 7.5-year follow-up. Plast Reconstr Surg. 2001;108:2108–2112; discussion 2113.
Tarpila E, Ghassemifar R, Fagrell D, et al.Capsular contracture with textured versus smooth saline-filled implants for breast augmentation: a prospective clinical study. Plast Reconstr Surg. 1997;99:1934–1939.
Burkhardt BR, Eades EThe effect of Biocell texturing and povidone-iodine irrigation on capsular contracture around saline-inflatable breast implants. Plast Reconstr Surg. 1995;96:1317–1325.
Burkhardt BR, Demas CPThe effect of Siltex texturing and povidone-iodine irrigation on capsular contracture around saline inflatable breast implants. Plast Reconstr Surg. 1994;93:123–128; discussion 129.
Asplund O, Gylbert L, Jurell G, et al.Textured or smooth implants for submuscular breast augmentation: a controlled study. Plast Reconstr Surg. 1996;97:1200–1206.
Hakelius L, Ohlsén LA clinical comparison of the tendency to capsular contracture between smooth and textured gel-filled silicone mammary implants. Plast Reconstr Surg. 1992;90:247–254.
Collis N, Coleman D, Foo IT, et al.Ten-year review of a prospective randomized controlled trial of textured versus smooth subglandular silicone gel breast implants. Plast Reconstr Surg. 2000;106:786–791.
Malata CM, Feldberg L, Coleman DJ, et al.Textured or smooth implants for breast augmentation? Three year follow-up of a prospective randomised controlled trial. Br J Plast Surg. 1997;50:99–105.
Poeppl N, Schreml S, Lichtenegger F, et al.Does the surface structure of implants have an impact on the formation of a capsular contracture? Aesthetic Plast Surg. 2007;31:133–139.
Coleman DJ, Foo IT, Sharpe DTTextured or smooth implants for breast augmentation? A prospective controlled trial. Br J Plast Surg. 1991;44:444–448.
Stevens WG, Nahabedian MY, Calobrace MB, et al.Risk factor analysis for capsular contracture: a 5-year Sientra study analysis using round, smooth, and textured implants for breast augmentation. Plast Reconstr Surg. 2013;132:1115–1123.
Chong SJ, Deva AKUnderstanding the etiology and prevention of capsular contracture: translating science into practice. Clin Plast Surg. 2015;42:427–436.
Jones P, Mempin M, Hu H, et al.The functional influence of breast implant outer shell morphology on bacterial attachment and growth. Plast Reconstr Surg. 2018;142:837–849.
Becherer B, de Boer M, Spronk P, et al.The Dutch breast implant registry (DBIR): registration of breast implant - associated anaplastic large cell lymphoma (BIA-ALCL), a proof of concept. Plast Reconstr Surg. 2019. In press.
Magnusson M, Beath KJ, Locke M, et al.The epidemiology of breast implant associated large cell lymphoma in Australia and New Zealand confirms the highest risk for grade 4 surface breast implants. Plast Reconstr Surg. 2019. In press.
U.S. Food and Drug Administration. Anaplastic large cell lymphoma (ALCL) in women with breast implants: preliminary FDA findings and analyses. Secondary anaplastic large cell lymphoma (ALCL) in women with breast implants: preliminary FDA findings and analyses. 2016. Available at: https://www.fda.gov/medicaldevices/productsandmedicalprocedures/implantsandprosthetics/breastimplants/ucm239995.htm. Accessed September 4, 2018.
de Boer M, van Leeuwen FE, Hauptmann M, et al.Breast implants and the risk of anaplastic large-cell lymphoma in the breast. JAMA Oncol. 2018;4:335–341.
de Jong D, Vasmel WL, de Boer JP, et al.Anaplastic large-cell lymphoma in women with breast implants. JAMA. 2008;300:2030–2035.
TGA. Breast implants and anaplastic large cell lymphoma. Information for consumers. What is the risk? Secondary Breast implants and anaplastic large cell lymphoma. Information for consumers. What is the risk? 2018. Available at: https://www.tga.gov.au/alert/breast-implants-and-anaplastic-large-cell-lymphoma. Accessed September 10, 2018.
McLaughlin JK, Lipworth L, Fryzek JP, et al.Long-term cancer risk among Swedish women with cosmetic breast implants: an update of a nationwide study. J Natl Cancer Inst. 2006;98:557–560.
Pukkala E, Boice JD Jr, Hovi SL, et al.Incidence of breast and other cancers among Finnish women with cosmetic breast implants, 1970-1999. J Long Term Eff Med Implants. 2002;12:271–279.
Ye X, Shokrollahi K, Rozen WM, et al.Anaplastic large cell lymphoma (ALCL) and breast implants: breaking down the evidence. Mutat Res Rev Mutat Res. 2014;762:123–132.
Clemens MW, Brody GS, Mahabir RC, et al.How to diagnose and treat breast implant-associated anaplastic large cell lymphoma. Plast Reconstr Surg. 2018;141:586e–599e.
Adams WP Jr, Culbertson EJ, Deva AK, et al.Macrotextured breast implants with defined steps to minimize bacterial contamination around the device: experience in 42,000 implants. Plast Reconstr Surg. 2017;140:427–431.
Clemens MW, Horwitz SMNCCN consensus guidelines for the diagnosis and management of breast implant-associated anaplastic large cell lymphoma. Aesthet Surg J. 2017;37:285–289.
Clemens MW, Miranda RN, Butler CEBreast implant informed consent should include the risk of anaplastic large cell lymphoma. Plast Reconstr Surg. 2016;137:1117–1122.
Blombery P, Thompson E, Ryland G, et al.Frequent activating STAT3 mutations and novel recurrent genomic abnormalities detected in breast implant-associated anaplastic large cell lymphoma Oncotarget. Oncotarget. 2018;9:36126–36136.
Pastorello RG, D’Almeida Costa F, Osório CABT, et al.Breast implant-associated anaplastic large cell lymphoma in a Li-FRAUMENI patient: a case report. Diagn Pathol. 2018;13:10.
Lee YS, Filie A, Arthur D, et al.Breast implant-associated anaplastic large cell lymphoma in a patient with Li-Fraumeni syndrome. Histopathology. 2015;67:925–927.