A systematic review of the HPV-attributable fraction of oropharyngeal squamous cell carcinomas in Germany.
Germany
HNC
HPV
OPSCC
prevalence
Journal
Cancer medicine
ISSN: 2045-7634
Titre abrégé: Cancer Med
Pays: United States
ID NLM: 101595310
Informations de publication
Date de publication:
04 2019
04 2019
Historique:
received:
02
11
2018
revised:
09
01
2019
accepted:
29
01
2019
pubmed:
2
3
2019
medline:
12
5
2020
entrez:
2
3
2019
Statut:
ppublish
Résumé
The prevalence of oropharyngeal squamous cell carcinoma (OPSCC) is increasing globally while the prevalence of other head and neck cancers is decreasing. The most likely reasons for this are a decreasing influence of smoking and the growing relevance of infections with the human papilloma virus (HPV) as a risk factor. A rise in the HPV-attributable fraction (HPV-AF) of OPSCC has been observed in many countries, yet a comprehensive review of prevalence rates and trends in Germany is lacking. To determine the current HPV-AF of OPSCC in Germany and to assess whether it has changed during the last decades, we performed a systematic literature review. We screened Medline and EMBASE for studies that reported the tumor HPV status of newly diagnosed OPSCC patients treated at medical centers in Germany by testing for both HPV DNA and p16
Identifiants
pubmed: 30821126
doi: 10.1002/cam4.2039
pmc: PMC6488137
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1908-1918Informations de copyright
© 2019 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.
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