The Effects of Cold Arm Width and Metal Deposition on the Performance of a U-Beam Electrothermal MEMS Microgripper for Biomedical Applications.

SOIMUMPs™ cold arm width electrothermal actuation metal deposition microelectromechanical systems (MEMS) microgrippers micromanipulation red blood cells single crystal silicon

Journal

Micromachines
ISSN: 2072-666X
Titre abrégé: Micromachines (Basel)
Pays: Switzerland
ID NLM: 101640903

Informations de publication

Date de publication:
28 Feb 2019
Historique:
received: 28 01 2019
revised: 24 02 2019
accepted: 25 02 2019
entrez: 3 3 2019
pubmed: 3 3 2019
medline: 3 3 2019
Statut: epublish

Résumé

Microelectromechanical systems (MEMS) have established themselves within various fields dominated by high-precision micromanipulation, with the most distinguished sectors being the microassembly, micromanufacturing and biomedical ones. This paper presents a horizontal electrothermally actuated 'hot and cold arm' microgripper design to be used for the deformability study of human red blood cells (RBCs). In this study, the width and layer composition of the cold arm are varied to investigate the effects of dimensional and material variation of the cold arm on the resulting temperature distribution, and ultimately on the achieved lateral displacement at the microgripper arm tips. The cold arm widths investigated are 14 μ m, 30 μ m, 55 μ m, 70 μ m and 100 μ m. A gold layer with a thin chromium adhesion promoter layer is deposited on the top surface of each of these cold arms to study its effect on the performance of the microgripper. The resultant ten microgripper design variants are fabricated using a commercially available MEMS fabrication technology known as a silicon-on-insulator multi-user MEMS process (SOIMUMPs)™. This process results in an overhanging 25 μ m thick single crystal silicon microgripper structure having a low aspect ratio (width:thickness) value compared to surface micromachined structures where structural thicknesses are of the order of 2 μ m. Finite element analysis was used to numerically model the microgripper structures and coupled electrothermomechanical simulations were implemented in CoventorWare ® . The numerical simulations took into account the temperature dependency of the coefficient of thermal expansion, the thermal conductivity and the electrical conductivity properties in order to achieve more reliable results. The fabricated microgrippers were actuated under atmospheric pressure and the experimental results achieved through optical microscopy studies conformed with those predicted by the numerical models. The gap opening and the temperature rise at the cell gripping zone were also compared for the different microgripper structures in this work, with the aim of identifying an optimal microgripper design for the deformability characterisation of RBCs.

Identifiants

pubmed: 30823372
pii: mi10030167
doi: 10.3390/mi10030167
pmc: PMC6470733
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Reach High Scholars Programme - Post-Doctoral Grants, Ministry for Education and Employment, Malta. The grant is part-financed by the European Union, Operational Programme II - Cohesion Policy 2014-2020 - European Social Fund
ID : Grant number 254/15/05

Références

Biomed Microdevices. 2009 Apr;11(2):421-7
pubmed: 19015993
Biomicrofluidics. 2014 Sep 17;8(5):051501
pubmed: 25332724
Micromachines (Basel). 2017 Dec 30;9(1):null
pubmed: 30393290
Micromachines (Basel). 2018 Mar 02;9(3):null
pubmed: 30424042

Auteurs

Marija Cauchi (M)

Department of Mechanical Engineering, Faculty of Engineering, University of Malta, MSD 2080 Msida, Malta. mcauc03@um.edu.mt.

Ivan Grech (I)

Department of Microelectronics and Nanoelectronics, Faculty of Information and Communication Technology, University of Malta, MSD 2080 Msida, Malta. ivan.grech@um.edu.mt.

Bertram Mallia (B)

Department of Metallurgy and Materials Engineering, Faculty of Engineering, University of Malta, MSD 2080 Msida, Malta. bertram.mallia@um.edu.mt.

Pierluigi Mollicone (P)

Department of Mechanical Engineering, Faculty of Engineering, University of Malta, MSD 2080 Msida, Malta. pierluigi.mollicone@um.edu.mt.

Nicholas Sammut (N)

Department of Microelectronics and Nanoelectronics, Faculty of Information and Communication Technology, University of Malta, MSD 2080 Msida, Malta. nicholas.sammut@um.edu.mt.

Classifications MeSH