Allergen Sensitization and Asthma Outcomes among World Trade Center Rescue and Recovery Workers.
WTC-related asthma
World Trade Center
allergen exposure
asthma control
asthma morbidity
asthma outcomes
asthma quality of life
immunoglobulin E
indoor allergens sensitization
mini asthma quality of life questionnaire
Journal
International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455
Informations de publication
Date de publication:
01 03 2019
01 03 2019
Historique:
received:
15
01
2019
revised:
15
02
2019
accepted:
22
02
2019
entrez:
3
3
2019
pubmed:
3
3
2019
medline:
3
7
2019
Statut:
epublish
Résumé
A large number of World Trade Center (WTC) rescue and recovery workers are affected by asthma. While physical and mental health comorbidities have been associated with poor asthma control in this population, the potential role of allergen sensitization is unknown. This study examined the association of indoor sensitization and exposure as a risk factor for increased asthma morbidity in WTC workers. We used data from a prospective cohort of 331 WTC workers with asthma. Sensitization to indoor allergens was assessed by measurement of antigen-specific serum immunoglobulin E (IgE) levels. We used validated tools to evaluate the exposure to indoor allergens. Asthma morbidity outcomes included level of control (Asthma Control Questionnaire, ACQ), quality of life (Asthma Quality of Life Questionnaire, AQLQ) and acute resource utilization. The prevalence of sensitization to cat, dog, mouse, dust mite, cockroach, and mold allergens were 33%, 21%, 17%, 40%, 17%, and 17%, respectively. Unadjusted and regression analyses showed no significant relationship between sensitization and increased asthma morbidity (
Identifiants
pubmed: 30823641
pii: ijerph16050737
doi: 10.3390/ijerph16050737
pmc: PMC6427816
pii:
doi:
Substances chimiques
Allergens
0
Types de publication
Journal Article
Research Support, U.S. Gov't, P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NIOSH CDC HHS
ID : U01 OH010405
Pays : United States
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