Feasibility and Construct Validation of the Patient Reported Outcomes Measurement Information System in Systemic Vasculitis.
Adult
Aged
Anti-Inflammatory Agents
/ therapeutic use
Cognition
/ physiology
Cross-Sectional Studies
Disability Evaluation
Fatigue
/ diagnosis
Feasibility Studies
Female
Humans
Longitudinal Studies
Male
Middle Aged
Pain
/ diagnosis
Patient Reported Outcome Measures
Quality of Life
Social Participation
Systemic Vasculitis
/ drug therapy
PATIENT-REPORTED OUTCOME MEASURES
VASCULITIS
Journal
The Journal of rheumatology
ISSN: 0315-162X
Titre abrégé: J Rheumatol
Pays: Canada
ID NLM: 7501984
Informations de publication
Date de publication:
08 2019
08 2019
Historique:
accepted:
26
11
2018
pubmed:
3
3
2019
medline:
17
9
2020
entrez:
3
3
2019
Statut:
ppublish
Résumé
The Patient Reported Outcome Measurement Information System (PROMIS) is a collection of item banks of self-reported health. This study assessed the feasibility and construct validity of using PROMIS instruments in vasculitis. Data from a multicenter longitudinal cohort of subjects with systemic vasculitis were used. Instruments from 10 PROMIS item banks were selected with direct involvement of patients. Subjects completed PROMIS instruments using computer adaptive testing (CAT). The Medical Outcomes Study Short Form-36 (SF-36) was also administered. Cross-sectional construct validity was assessed by calculating correlations of PROMIS scores with SF-36 measures and physician and patient global scores for disease activity. Longitudinal construct validity was assessed by correlations of between-visit differences in PROMIS scores with differences in other measures. During the study period, 973 subjects came for 2306 study visits and the PROMIS collection was completed at 2276 (99%) of visits. The median time needed to complete each PROMIS instrument ranged from 40 to 55 s. PROMIS instruments correlated cross-sectionally with individual scales of the SF-36, most strongly with subscales of the SF-36 addressing the same domain as the PROMIS instrument. For example, PROMIS fatigue correlated with both the physical component score (PCS; r = -0.65) and with the mental component score (MCS; r = -0.54). PROMIS physical function correlated strongly with PCS (r = 0.81) but weakly with MCS (r = 0.29). Weaker correlations were observed longitudinally between change in PROMIS scores with change in PCS and MCS. Collection of data using CAT PROMIS instruments is feasible among patients with vasculitis and has some cross-sectional and longitudinal construct validity.
Identifiants
pubmed: 30824648
pii: jrheum.171405
doi: 10.3899/jrheum.171405
pmc: PMC6726391
mid: NIHMS1515272
doi:
Substances chimiques
Anti-Inflammatory Agents
0
Types de publication
Journal Article
Multicenter Study
Research Support, N.I.H., Extramural
Validation Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
928-934Subventions
Organisme : Medical Research Council
ID : MR/N011775/1
Pays : United Kingdom
Organisme : NCATS NIH HHS
ID : U2C TR002818
Pays : United States
Organisme : NCRR NIH HHS
ID : U54 RR019497
Pays : United States
Organisme : NIAMS NIH HHS
ID : R01 AR064153
Pays : United States
Organisme : NIAMS NIH HHS
ID : U54 AR057319
Pays : United States
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