The Dynamic Structures of the Type IV Pilus.

Fimbriae Proteins / chemistry Fimbriae, Bacterial / chemistry Flagella / chemistry Protein Transport Type II Secretion Systems

Journal

Microbiology spectrum
ISSN: 2165-0497
Titre abrégé: Microbiol Spectr
Pays: United States
ID NLM: 101634614

Informations de publication

Date de publication:
03 2019
Historique:
entrez: 3 3 2019
pubmed: 3 3 2019
medline: 13 4 2019
Statut: ppublish

Résumé

Type IV pilus (T4P)-like systems have been identified in almost every major phylum of prokaryotic life. They include the type IVa pilus (T4aP), type II secretion system (T2SS), type IVb pilus (T4bP), Tad/Flp pilus, Com pilus, and archaeal flagellum (archaellum). These systems are used for adhesion, natural competence, phage adsorption, folded-protein secretion, surface sensing, swimming motility, and twitching motility. The T4aP allows for all of these functions except swimming and is therefore a good model system for understanding T4P-like systems. Recent structural analyses have revolutionized our understanding of how the T4aP machinery assembles and functions. Here we review the structure and function of the T4aP.

Identifiants

DOI: 10.1128/microbiolspec.PSIB-0006-2018 PMID: 30825300
pubmed: 30825300
doi: 10.1128/microbiolspec.PSIB-0006-2018
doi:

Substances chimiques

Type II Secretion Systems 0
Fimbriae Proteins 147680-16-8

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : CIHR
ID : MOP 93585
Pays : Canada

Auteurs

Matthew McCallum (M)

Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada.
Program in Molecular Medicine, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.

Lori L Burrows (LL)

Department of Biochemistry and Biomedical Sciences and the Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, ON L8N 3Z5, Canada.

P Lynne Howell (PL)

Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada.
Program in Molecular Medicine, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de la membrane externe bactérienne › Protéines de fimbriae › The Dynamic Structures of the Type IV Pilus.
questionsmedicales.fr › Structures bactériennes › Fimbriae bactériens › The Dynamic Structures of the Type IV Pilus.
questionsmedicales.fr › Cellules › Structures cellulaires › Prolongements cytoplasmiques › Flagelles › The Dynamic Structures of the Type IV Pilus.
questionsmedicales.fr › Métabolisme › Transport biologique › Transport des protéines › The Dynamic Structures of the Type IV Pilus.
questionsmedicales.fr › Structures macromoléculaires › Complexes multiprotéiques › Systèmes de translocation des protéines › Systèmes bactériens de sécrétion › Systèmes de sécrétion de type II › The Dynamic Structures of the Type IV Pilus.