Endocrine disruptors of inhibiting testicular 3β-hydroxysteroid dehydrogenase.

17-Hydroxysteroid Dehydrogenases / antagonists & inhibitors Endocrine Disruptors / pharmacology Humans Male Multienzyme Complexes / antagonists & inhibitors Progesterone Reductase / antagonists & inhibitors Steroid Isomerases / antagonists & inhibitors Testis / enzymology
3β-hydroxysteroid dehydrogenase Environmental endocrine disruptors Phthalates Polyphenols Steroidogenesis Testosterone production

Journal

Chemico-biological interactions
ISSN: 1872-7786
Titre abrégé: Chem Biol Interact
Pays: Ireland
ID NLM: 0227276

Informations de publication

Date de publication:
25 Apr 2019
Historique:
received: 26 12 2018
revised: 09 02 2019
accepted: 26 02 2019
pubmed: 4 3 2019
medline: 16 4 2019
entrez: 4 3 2019
Statut: ppublish

Résumé

Testicular 3β-hydroxysteroid dehydrogenase (HSD3B) is a steroidogenic enzyme, catalyzing the conversion of 3β-hydroxysteroids into 3-keto-steroids. Two distinct isoforms in the human are cloned, HSD3B1 and HSD3B2, and HSD3B2 is located in the testis. HSD3B2 is a two-substrate enzyme, which binds to cofactor NAD

Identifiants

DOI: 10.1016/j.cbi.2019.02.027 PMID: 30826252
pubmed: 30826252
pii: S0009-2797(18)31780-0
doi: 10.1016/j.cbi.2019.02.027
pii:
doi:

Substances chimiques

3 beta-hydroxysteroid oxidoreductase-delta(5) 3-ketosteroid isomerase 0
Endocrine Disruptors 0
Multienzyme Complexes 0
17-Hydroxysteroid Dehydrogenases EC 1.1.-
3 beta-hydroxysteroid dehydrogenase type II EC 1.1.1.145
Progesterone Reductase EC 1.1.1.145
3 (or 17)-beta-hydroxysteroid dehydrogenase EC 1.1.1.51
Steroid Isomerases EC 5.3.3.-

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

90-97

Informations de copyright

Copyright © 2019. Published by Elsevier B.V.

Auteurs

Song Zhang (S)

Department of Obstetrics and Gynecology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

Jiaying Mo (J)

Department of Obstetrics and Gynecology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

Yiyan Wang (Y)

Department of Anesthesiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

Chaobo Ni (C)

Department of Anesthesiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

Xiaoheng Li (X)

Department of Obstetrics and Gynecology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

Qiqi Zhu (Q)

Department of Anesthesiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

Ren-Shan Ge (RS)

Department of Obstetrics and Gynecology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China; Department of Anesthesiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China. Electronic address: r_ge@yahoo.com.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Alcohol oxidoreductases › Hydroxysteroid dehydrogenases › 17-Hydroxysteroid dehydrogenases › Endocrine disruptors of inhibiting testicular...
questionsmedicales.fr › Actions chimiques et utilisations › Actions toxiques › Perturbateurs endocriniens › Endocrine disruptors of inhibiting testicular...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Endocrine disruptors of inhibiting testicular...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Complexes multienzymatiques › Endocrine disruptors of inhibiting testicular...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Alcohol oxidoreductases › NAD (+) and NADP (+) dependent Alcohol oxidoreductases › Progesterone reductase › Endocrine disruptors of inhibiting testicular...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Isomerases › Intramolecular oxidoreductases › Carbon-carbon double bond isomerases › Steroid isomerases › Endocrine disruptors of inhibiting testicular...
questionsmedicales.fr › Système endocrine › Glandes endocrines › Gonades › Testicule › Endocrine disruptors of inhibiting testicular...