Giant Cell Arteritis (GCA): Pathogenesis, Clinical Aspects and Treatment Approaches.

Autoimmune disease ENT GCA audiovestibular abnormalities hearing loss polymyalgia rheumatica vasculitis.

Journal

Current rheumatology reviews
ISSN: 1875-6360
Titre abrégé: Curr Rheumatol Rev
Pays: United Arab Emirates
ID NLM: 101261938

Informations de publication

Date de publication:
2019
Historique:
received: 01 10 2018
revised: 30 01 2019
accepted: 13 02 2019
pubmed: 5 3 2019
medline: 24 4 2020
entrez: 5 3 2019
Statut: ppublish

Résumé

Giant Cell Arteritis (GCA), or Horton's Arteritis, is a chronic form of vasculitis of the large and medium vessels, especially involving the extracranial branches of the carotid arteries, in particular, the temporal artery, with the involvement of the axillary, femoral and iliac arteries too. Arterial wall inflammation leads to luminal occlusion and tissue ischemia, which is responsible for the clinical manifestations of the disease. A substantial number of patients affected by GCA present head and neck symptoms, including ocular, neurological and otorhinolaryngological manifestations. The aim of this article is to present pathogenesis, clinical aspects and treatment approaches of GCA manifestations.

Identifiants

pubmed: 30827250
pii: CRR-EPUB-96907
doi: 10.2174/1573397115666190227194014
doi:

Substances chimiques

Adrenal Cortex Hormones 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

259-268

Informations de copyright

Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Auteurs

Andrea Ciofalo (A)

Otorhinolaryngology Department, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico, 151 - 00161, Rome, Italy.

Giampiero Gulotta (G)

Otorhinolaryngology Department, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico, 151 - 00161, Rome, Italy.

Giannicola Iannella (G)

Otorhinolaryngology Department, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico, 151 - 00161, Rome, Italy.

Benedetta Pasquariello (B)

Otorhinolaryngology Department, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico, 151 - 00161, Rome, Italy.

Alessandra Manno (A)

Otorhinolaryngology Department, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico, 151 - 00161, Rome, Italy.

Diletta Angeletti (D)

Otorhinolaryngology Department, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico, 151 - 00161, Rome, Italy.

Annalisa Pace (A)

Otorhinolaryngology Department, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico, 151 - 00161, Rome, Italy.

Antonio Greco (A)

Otorhinolaryngology Department, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico, 151 - 00161, Rome, Italy.

Giancarlo Altissimi (G)

Otorhinolaryngology Department, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico, 151 - 00161, Rome, Italy.

Marco de Vincentiis (M)

Otorhinolaryngology Department, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico, 151 - 00161, Rome, Italy.

Giuseppe Magliulo (G)

Otorhinolaryngology Department, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico, 151 - 00161, Rome, Italy.

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Classifications MeSH