Blood culture result profile and antimicrobial resistance pattern: a report from neonatal intensive care unit (NICU), Asella teaching and referral hospital, Asella, south East Ethiopia.


Journal

Antimicrobial resistance and infection control
ISSN: 2047-2994
Titre abrégé: Antimicrob Resist Infect Control
Pays: England
ID NLM: 101585411

Informations de publication

Date de publication:
2019
Historique:
received: 15 12 2018
accepted: 01 02 2019
entrez: 5 3 2019
pubmed: 5 3 2019
medline: 21 4 2020
Statut: epublish

Résumé

Antimicrobial resistance is one of the major public health emergencies worldwide, and this trend didn't spare developing countries like Ethiopia. The objective of this study was to evaluate patterns of bacterial isolates and local antimicrobial susceptibility patterns in neonatal sepsis. A hospital based observational study was conducted from April 2016 to May 2017 in Asella teaching and referral hospital (ATRH). A total of 303 neonates with clinical sepsis were included. Collected data were entered into EPI-INFO version 3.5.1 for cleanup; and then exported to SPSS version 21 for further analysis. Frequencies and proportion were used to describe the study population in relation to relevant variables. Bacterial growth was detected in 88 (29.4%) of blood cultures. Predominantly isolated bacteria were coagulase negative CoNS,

Sections du résumé

Background
Antimicrobial resistance is one of the major public health emergencies worldwide, and this trend didn't spare developing countries like Ethiopia. The objective of this study was to evaluate patterns of bacterial isolates and local antimicrobial susceptibility patterns in neonatal sepsis.
Methods
A hospital based observational study was conducted from April 2016 to May 2017 in Asella teaching and referral hospital (ATRH). A total of 303 neonates with clinical sepsis were included. Collected data were entered into EPI-INFO version 3.5.1 for cleanup; and then exported to SPSS version 21 for further analysis. Frequencies and proportion were used to describe the study population in relation to relevant variables.
Results
Bacterial growth was detected in 88 (29.4%) of blood cultures. Predominantly isolated bacteria were coagulase negative
Conclusion
CoNS,

Identifiants

pubmed: 30828446
doi: 10.1186/s13756-019-0486-6
pii: 486
pmc: PMC6383240
doi:

Substances chimiques

Anti-Bacterial Agents 0

Types de publication

Journal Article Observational Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

42

Déclaration de conflit d'intérêts

The research proposal was presented and approved by the Institutional Review Board of Arsi University and ethical clearance was obtained with ethical clearance certificate number of CoHS/CS/001/2016/17. Individual verbal consent of participation was obtained from mothers/ care givers of eligible neonates before starting interviews/laboratory sampling. The participation was purely voluntary and confidentiality and privacy were maintained by conducting interviews in separate spaces whenever possible. Benefits of the laboratory test were clearly communicated to mothers/care givers and for patients whose blood culture results showed positive growth, susceptibility-based antibiotics were started.Not applicable.The authors declare that there is no competing and conflict of interests.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Références

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Auteurs

Abebe Sorsa (A)

Arsi University Asella College of Health Science, Asella, Ethiopia.

Jonas Früh (J)

Hirsch-Institute of Tropical Medicine, Asella, Ethiopia.

Loraine Stötter (L)

Hirsch-Institute of Tropical Medicine, Asella, Ethiopia.

Sileshi Abdissa (S)

Arsi University Asella College of Health Science, Asella, Ethiopia.

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Classifications MeSH