Gold-Catalyzed Cyclisation by 1,4-Dioxidation.
cyclization
diphenylsulfoxide
diynes
gold
ynamides
Journal
Chemistry (Weinheim an der Bergstrasse, Germany)
ISSN: 1521-3765
Titre abrégé: Chemistry
Pays: Germany
ID NLM: 9513783
Informations de publication
Date de publication:
17 Jul 2019
17 Jul 2019
Historique:
received:
03
03
2019
pubmed:
5
3
2019
medline:
5
3
2019
entrez:
5
3
2019
Statut:
ppublish
Résumé
Amide-substituted diynes were cyclized in the presence of a cationic gold catalyst and an external nucleophile leading to 1-indenones and 1-iminoindenones. The electron-donating features of the nitrogen atom enable the formation of a reactive ketene iminium ion, which can be trapped by either diphenyl sulfoxide or anthranil as nucleophiles in a subsequent oxidation step, providing substituted inden-1-on-3-carboxamides.
Identifiants
pubmed: 30829424
doi: 10.1002/chem.201900996
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
9385-9389Informations de copyright
© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.