An

ADME DMPK LC-MS/MS anti-TB chemotherapy decoquinate pharmacokinetics tuberculosis

Journal

Frontiers in pharmacology
ISSN: 1663-9812
Titre abrégé: Front Pharmacol
Pays: Switzerland
ID NLM: 101548923

Informations de publication

Date de publication:
2019
Historique:
received: 22 11 2018
accepted: 31 01 2019
entrez: 6 3 2019
pubmed: 6 3 2019
medline: 6 3 2019
Statut: epublish

Résumé

Tuberculosis (TB) is currently the leading cause of mortality due to an infectious disease, despite the existence of multiple effective first-line and second-line drugs. The current anti-TB regimen requires a prolonged treatment period of around 6 months and is only efficacious against drug-sensitive strains of

Identifiants

pubmed: 30833898
doi: 10.3389/fphar.2019.00120
pmc: PMC6387968
doi:

Types de publication

Journal Article

Langues

eng

Pagination

120

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Auteurs

Lloyd Tanner (L)

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

Richard K Haynes (RK)

Centre of Excellence for Pharmaceutical Sciences, Faculty of Health Sciences, North-West University, Potchefstroom, South Africa.

Lubbe Wiesner (L)

Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

Classifications MeSH