Prevalence of integron classes in Gram-negative clinical isolated bacteria in Iran: a systematic review and meta-analysis.
Bacteria
Integron
Iran
MDR
Meta-Analysis
Journal
Iranian journal of basic medical sciences
ISSN: 2008-3866
Titre abrégé: Iran J Basic Med Sci
Pays: Iran
ID NLM: 101517966
Informations de publication
Date de publication:
Feb 2019
Feb 2019
Historique:
entrez:
6
3
2019
pubmed:
6
3
2019
medline:
6
3
2019
Statut:
ppublish
Résumé
Integrons, as a potential element in the distribution and maintenance of drug resistance, have thoroughly been established. It is known that the high prevalence of integrons in multidrug-resistant (MDR) clinical isolates has become a serious public health concern. The objective of the present study was to determine the frequency of different classes of integrons in clinical isolates in Iran. Electronic global databases were systematically searched. The raw data for integrons among bacterial isolates were collected and their prevalence was analyzed using Comprehensive Meta-Analysis V2.0 (Biostat, Englewood, NJ, USA) software. In a comprehensive literature review, 29 eligible studies were determined with their meta-analyses indicating the prevalence of integron class 1 to be 41% (95% CI 36.3-46.1) and integron class 2 as 17.7% (95% CI 13-23.3) in Gram-negative bacteria. The highest prevalence of integron class 1 was reported in The current systematic review demonstrated the significant presence of integrons among clinical isolates. Our analysis showed that measures such as estimates of the prevalence of this transposable element and diligence in continued surveillance might be necessary to prevent its spread.
Identifiants
pubmed: 30834075
doi: 10.22038/ijbms.2018.32052.7697
pmc: PMC6396983
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
118-127Déclaration de conflit d'intérêts
We declare no conflict of interest for the authors of the present study.
Références
Antimicrob Agents Chemother. 2001 Mar;45(3):723-6
pubmed: 11181350
Antimicrob Agents Chemother. 2001 Nov;45(11):2991-3000
pubmed: 11600347
J Bacteriol. 2001 Nov;183(22):6699-706
pubmed: 11673443
Spine (Phila Pa 1976). 2003 Jun 15;28(12):1290-9
pubmed: 12811274
Clin Microbiol Infect. 2004 Apr;10(4):272-88
pubmed: 15059115
Antimicrob Agents Chemother. 1992 Mar;36(3):611-5
pubmed: 1622171
Nat Rev Microbiol. 2006 Aug;4(8):608-20
pubmed: 16845431
Trends Microbiol. 2007 Jul;15(7):301-9
pubmed: 17566739
BMC Infect Dis. 2007 Jun 22;7:62
pubmed: 17587439
Jpn J Infect Dis. 2008 Jan;61(1):85-8
pubmed: 18219144
FEMS Microbiol Rev. 2009 Jul;33(4):757-84
pubmed: 19416365
Ann Intern Med. 2009 Aug 18;151(4):W65-94
pubmed: 19622512
Microb Drug Resist. 2009 Sep;15(3):179-84
pubmed: 19728775
PLoS Genet. 2010 Jan;6(1):e1000793
pubmed: 20066027
Annu Rev Genet. 2010;44:141-66
pubmed: 20707672
Microbiol Mol Biol Rev. 2010 Sep;74(3):417-33
pubmed: 20805405
Jpn J Infect Dis. 2010 Nov;63(6):417-21
pubmed: 21099092
Int J Antimicrob Agents. 2011 May;37(5):489-90
pubmed: 21419606
FEMS Microbiol Rev. 2011 Sep;35(5):820-55
pubmed: 21564142
Pol J Microbiol. 2011;60(2):163-8
pubmed: 21905635
Pol J Microbiol. 2011;60(2):169-74
pubmed: 21905636
Iran J Microbiol. 2011 Sep;3(3):112-7
pubmed: 22347592
Jpn J Infect Dis. 2012;65(3):256-9
pubmed: 22627310
Pol J Microbiol. 2012;61(1):57-60
pubmed: 22708347
Microb Drug Resist. 2012 Dec;18(6):546-9
pubmed: 22816551
Ann N Y Acad Sci. 2012 Sep;1267:71-8
pubmed: 22954219
Foodborne Pathog Dis. 2013 Mar;10(3):237-42
pubmed: 23489046
Asian Pac J Trop Biomed. 2013 Feb;3(2):140-5
pubmed: 23593593
Braz J Microbiol. 2011 Oct;42(4):1308-13
pubmed: 24031757
Braz J Microbiol. 2014 Jan 15;44(3):849-54
pubmed: 24516451
Microbiol Mol Biol Rev. 2014 Jun;78(2):257-77
pubmed: 24847022
Jundishapur J Microbiol. 2014 Feb;7(2):e8747
pubmed: 25147670
Osong Public Health Res Perspect. 2014 Aug;5(4):193-8
pubmed: 25379369
Microb Drug Resist. 2015 Aug;21(4):435-40
pubmed: 25658172
Pathog Glob Health. 2015;109(7):309-18
pubmed: 26343252
Jundishapur J Microbiol. 2015 Jul 25;8(7):e27021
pubmed: 26421140
Turk J Med Sci. 2015;45(4):789-93
pubmed: 26422847
Crit Rev Food Sci Nutr. 2017 Sep 2;57(13):2857-2876
pubmed: 26464037
Adv Pharm Bull. 2015 Sep;5(3):335-42
pubmed: 26504755
PLoS One. 2017 Feb 7;12(2):e0169617
pubmed: 28170400
J Infect. 2017 Jun;74(6):545-554
pubmed: 28366687
Biomedicine (Taipei). 2018 Mar;8(1):2
pubmed: 29480797