Histamine releasing factor and elongation factor 1 alpha secreted via malaria parasites extracellular vesicles promote immune evasion by inhibiting specific T cell responses.
Animals
Antigen Presentation
/ immunology
Antigens
/ genetics
Biomarkers, Tumor
/ genetics
CD4-Positive T-Lymphocytes
/ immunology
Cell Proliferation
/ genetics
Extracellular Vesicles
/ genetics
Humans
Immune Evasion
/ genetics
Malaria
/ genetics
Peptide Elongation Factor 1
/ genetics
Plasmodium berghei
/ genetics
T-Lymphocytes
/ immunology
Tumor Protein, Translationally-Controlled 1
T cells
extracellular vesicles
immune evasion
immunosuppression
malaria
Journal
Cellular microbiology
ISSN: 1462-5822
Titre abrégé: Cell Microbiol
Pays: India
ID NLM: 100883691
Informations de publication
Date de publication:
07 2019
07 2019
Historique:
received:
17
02
2019
revised:
22
02
2019
accepted:
25
02
2019
pubmed:
6
3
2019
medline:
1
9
2020
entrez:
6
3
2019
Statut:
ppublish
Résumé
Protozoan pathogens secrete nanosized particles called extracellular vesicles (EVs) to facilitate their survival and chronic infection. Here, we show the inhibition by Plasmodium berghei NK65 blood stage-derived EVs of the proliferative response of CD4
Substances chimiques
Antigens
0
Biomarkers, Tumor
0
Peptide Elongation Factor 1
0
Tumor Protein, Translationally-Controlled 1
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e13021Informations de copyright
© 2019 John Wiley & Sons Ltd.