Chromosome Segregation: Poor Supervision in the Early Stage of Life.

Aneuploidy Animals Cell Cycle Checkpoints Cell Size Chromosome Segregation Chromosomes Mice

Journal

Current biology : CB
ISSN: 1879-0445
Titre abrégé: Curr Biol
Pays: England
ID NLM: 9107782

Informations de publication

Date de publication:
04 03 2019
Historique:
entrez: 6 3 2019
pubmed: 6 3 2019
medline: 4 12 2019
Statut: ppublish

Résumé

Abnormal chromosome number, or aneuploidy, is common in early mammalian embryos, although the underlying cell biological basis is still incompletely understood. New research reveals that cells often fail to wait for all chromosomes to properly attach to the spindle machinery before segregation, explaining why early embryonic cell cycles are so error-prone.

Identifiants

DOI: 10.1016/j.cub.2019.01.036 PMID: 30836084
pubmed: 30836084
pii: S0960-9822(19)30065-X
doi: 10.1016/j.cub.2019.01.036
pii:
doi:

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

R156-R158

Subventions

Organisme : NIGMS NIH HHS
ID : R35 GM122475
Pays : United States

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2019 Elsevier Ltd. All rights reserved.

Auteurs

Takashi Akera (T)

Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.

Michael A Lampson (MA)

Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: lampson@sas.upenn.edu.

Articles similaires

Evaluating the efficacy of telesurgery with dual console SSI Mantra Surgical Robotic System: experiment on animal model and clinical trials.

Sudhir Prem Srivastava, Vishwajyoti Pascual Srivastava, Avinesh Singh et al.
1.00
Robotic Surgical Procedures Animals Humans Telemedicine Models, Animal

Odour generalisation and detection dog training.

Lyn Caldicott, Thomas W Pike, Helen E Zulch et al.
1.00
Animals Odorants Dogs Generalization, Psychological Smell

FBXO22 inhibits colitis and colorectal carcinogenesis by regulating the degradation of the S2448-phosphorylated form of mTOR.

Minle Li, Xuan Chen, Pengfei Qu et al.
1.00
Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice

Use of organic material provided by an automatic enrichment device by weaner pigs and its influence on tail lesions.

Philipp Heseker, Jeanette Probst, Stefanie Ammer et al.
1.00
Animals Tail Swine Behavior, Animal Animal Husbandry

Classifications MeSH

questionsmedicales.fr › Phénomènes génétiques › Ploïdies › Aneuploïdie › Chromosome Segregation: Poor Supervision in...
questionsmedicales.fr › Eucaryotes › Animaux › Chromosome Segregation: Poor Supervision in...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Cycle cellulaire › Points de contrôle du cycle cellulaire › Chromosome Segregation: Poor Supervision in...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Taille de la cellule › Chromosome Segregation: Poor Supervision in...
questionsmedicales.fr › Phénomènes génétiques › Division du noyau cellulaire › Ségrégation des chromosomes › Chromosome Segregation: Poor Supervision in...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Chromosomes › Chromosome Segregation: Poor Supervision in...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Chromosome Segregation: Poor Supervision in...