Changes in Persistent Asthma Care and Outcomes From 2006 to 2016 in France.


Journal

The journal of allergy and clinical immunology. In practice
ISSN: 2213-2201
Titre abrégé: J Allergy Clin Immunol Pract
Pays: United States
ID NLM: 101597220

Informations de publication

Date de publication:
Historique:
received: 10 09 2018
revised: 15 02 2019
accepted: 15 02 2019
pubmed: 6 3 2019
medline: 8 9 2020
entrez: 6 3 2019
Statut: ppublish

Résumé

Changes in asthma care need to be documented at arrival of biotherapies. To characterize changes in asthma care and outcomes in patients with persistent asthma. Repeated transversal analyses were conducted on a historical cohort using the French national claims data over 10 years. Patients aged 18 to 40 years with either 1 or more (any-use population) or 4 or more (high-use population) yearly dispensings of controller therapy were selected. Clinical and demographic features were characterized, and comparisons were made between 2006 and 2016 to assess temporal changes in asthma therapy, health care resource utilization, and outcomes. In 2016, prevalent use of controller therapy was 5.2% (any-use population) and 0.8% (high-use population) of the population aged 18 to 40 years. In the any-use population, the use of long-acting β Changes in persistent asthma care included replacement of inhaled corticosteroids by fixed-dose combinations, decreased use of long-acting β

Sections du résumé

BACKGROUND
Changes in asthma care need to be documented at arrival of biotherapies.
OBJECTIVES
To characterize changes in asthma care and outcomes in patients with persistent asthma.
METHODS
Repeated transversal analyses were conducted on a historical cohort using the French national claims data over 10 years. Patients aged 18 to 40 years with either 1 or more (any-use population) or 4 or more (high-use population) yearly dispensings of controller therapy were selected. Clinical and demographic features were characterized, and comparisons were made between 2006 and 2016 to assess temporal changes in asthma therapy, health care resource utilization, and outcomes.
RESULTS
In 2016, prevalent use of controller therapy was 5.2% (any-use population) and 0.8% (high-use population) of the population aged 18 to 40 years. In the any-use population, the use of long-acting β
CONCLUSIONS
Changes in persistent asthma care included replacement of inhaled corticosteroids by fixed-dose combinations, decreased use of long-acting β

Identifiants

pubmed: 30836232
pii: S2213-2198(19)30202-8
doi: 10.1016/j.jaip.2019.02.025
pii:
doi:

Substances chimiques

Adrenal Cortex Hormones 0
Adrenergic beta-Agonists 0
Anti-Asthmatic Agents 0
Leukotriene Antagonists 0
Omalizumab 2P471X1Z11

Types de publication

Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

1858-1867

Informations de copyright

Copyright © 2019 The Authors. Published by Elsevier Inc. All rights reserved.

Auteurs

Manon Belhassen (M)

PELyon, PharmacoEpidemiology Lyon, Lyon, France. Electronic address: manon.belhassen@univ-lyon1.fr.

Maëva Nolin (M)

PELyon, PharmacoEpidemiology Lyon, Lyon, France.

Anjan Nibber (A)

University of Oxford Medical School, Oxford, United Kingdom.

Marine Ginoux (M)

PELyon, PharmacoEpidemiology Lyon, Lyon, France.

Gilles Devouassoux (G)

Respiratory Medicine, Croix Rousse University Hospital, and EA7426 University Claude Bernard Lyon-1, Lyon, France.

Eric Van Ganse (E)

PELyon, PharmacoEpidemiology Lyon, Lyon, France; Respiratory Medicine, Croix Rousse University Hospital, and EA7426 University Claude Bernard Lyon-1, Lyon, France; HESPER 7425, Health Services and Performance Research, University Claude Bernard Lyon 1, Lyon, France.

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Classifications MeSH